Sepp-Lorenzino L - Search Results

1

Antiangiogenic agents targeting vascular endothelial growth factor and its receptors in clinical development.

Sepp-Lorenzino L, Thomas KA. Sepp-Lorenzino L, et al. Expert Opin Investig Drugs. 2002 Oct;11(10):1447-65. doi: 10.1517/13543784.11.10.1447. Expert Opin Investig Drugs. 2002. PMID: 12387705 Review.

2

Potent 2-[(pyrimidin-4-yl)amine}-1,3-thiazole-5-carbonitrile-based inhibitors of VEGFR-2 (KDR) kinase.

Sisko JT, Tucker TJ, Bilodeau MT, Buser CA, Ciecko PA, Coll KE, Fernandes C, Gibbs JB, Koester TJ, Kohl N, Lynch JJ, Mao X, McLoughlin D, Miller-Stein CM, Rodman LD, Rickert KW, Sepp-Lorenzino L, Shipman JM, Thomas KA, Wong BK, Hartman GD. Sisko JT, et al. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1146-50. doi: 10.1016/j.bmcl.2005.11.089. Epub 2005 Dec 20. Bioorg Med Chem Lett. 2006. PMID: 16368234

3

Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling.

Hardwick JS, Yang Y, Zhang C, Shi B, McFall R, Koury EJ, Hill SL, Dai H, Wasserman R, Phillips RL, Weinstein EJ, Kohl NE, Severino ME, Lamb JR, Sepp-Lorenzino L. Hardwick JS, et al. Mol Cancer Ther. 2005 Mar;4(3):413-25. doi: 10.1158/1535-7163.MCT-04-0209. Mol Cancer Ther. 2005. PMID: 15767550

4

Potent N-(1,3-thiazol-2-yl)pyridin-2-amine vascular endothelial growth factor receptor tyrosine kinase inhibitors with excellent pharmacokinetics and low affinity for the hERG ion channel.

Bilodeau MT, Balitza AE, Koester TJ, Manley PJ, Rodman LD, Buser-Doepner C, Coll KE, Fernandes C, Gibbs JB, Heimbrook DC, Huckle WR, Kohl N, Lynch JJ, Mao X, McFall RC, McLoughlin D, Miller-Stein CM, Rickert KW, Sepp-Lorenzino L, Shipman JM, Subramanian R, Thomas KA, Wong BK, Yu S, Hartman GD. Bilodeau MT, et al. J Med Chem. 2004 Dec 2;47(25):6363-72. doi: 10.1021/jm049697f. J Med Chem. 2004. PMID: 15566305

5

Design and synthesis of 3,7-diarylimidazopyridines as inhibitors of the VEGF-receptor KDR.

Wu Z, Fraley ME, Bilodeau MT, Kaufman ML, Tasber ES, Balitza AE, Hartman GD, Coll KE, Rickert K, Shipman J, Shi B, Sepp-Lorenzino L, Thomas KA. Wu Z, et al. Bioorg Med Chem Lett. 2004 Feb 23;14(4):909-12. doi: 10.1016/j.bmcl.2003.12.007. Bioorg Med Chem Lett. 2004. PMID: 15012992

6

A novel orally bioavailable inhibitor of kinase insert domain-containing receptor induces antiangiogenic effects and prevents tumor growth in vivo.

Sepp-Lorenzino L, Rands E, Mao X, Connolly B, Shipman J, Antanavage J, Hill S, Davis L, Beck S, Rickert K, Coll K, Ciecko P, Fraley M, Hoffman W, Hartman G, Heimbrook D, Gibbs J, Kohl N, Thomas K. Sepp-Lorenzino L, et al. Cancer Res. 2004 Jan 15;64(2):751-6. doi: 10.1158/0008-5472.can-03-2871. Cancer Res. 2004. PMID: 14744794

7

Angiogenesis-research frontiers. A basic science conference of the New York Academy of Medicine.

Sepp-Lorenzino L, Pan BS. Sepp-Lorenzino L, et al. Expert Opin Investig Drugs. 2000 Apr;9(4):929-35. doi: 10.1517/13543784.9.4.929. Expert Opin Investig Drugs. 2000. PMID: 11185425

8

92nd Annual Meeting of the American Association for Cancer Research. 24-28 March, 2001, New Orleans, Louisiana, USA.

Buser C, Takaki T, Sepp-Lorenzino L. Buser C, et al. Expert Opin Investig Drugs. 2001 Jun;10(6):1173-93. doi: 10.1517/13543784.10.6.1173. Expert Opin Investig Drugs. 2001. PMID: 11785454

9

Challenges and opportunities for local and systemic delivery of siRNA and antisense oligonucleotides.

Sepp-Lorenzino L, Ruddy M. Sepp-Lorenzino L, et al. Clin Pharmacol Ther. 2008 Nov;84(5):628-32. doi: 10.1038/clpt.2008.174. Epub 2008 Sep 17. Clin Pharmacol Ther. 2008. PMID: 18800034 No abstract available.

10

Farnesyltransferase inhibitors and anti-Ras therapy.

Gibbs JB, Kohl NE, Koblan KS, Omer CA, Sepp-Lorenzino L, Rosen N, Anthony NJ, Conner MW, deSolms SJ, Williams TM, Graham SL, Hartman GD, Oliff A. Gibbs JB, et al. Breast Cancer Res Treat. 1996;38(1):75-83. doi: 10.1007/BF01803786. Breast Cancer Res Treat. 1996. PMID: 8825125 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

Search Page

Search Results