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The Gut Microbiota Metabolite Succinate Promotes Adipose Tissue Browning in Crohn's Disease.
Monfort-Ferré D, Caro A, Menacho M, Martí M, Espina B, Boronat-Toscano A, Nuñez-Roa C, Seco J, Bautista M, Espín E, Megía A, Vendrell J, Fernández-Veledo S, Serena C. Monfort-Ferré D, et al. Among authors: serena c. J Crohns Colitis. 2022 Nov 1;16(10):1571-1583. doi: 10.1093/ecco-jcc/jjac069. J Crohns Colitis. 2022. PMID: 35554517 Free PMC article.
Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans.
Ceperuelo-Mallafré V, Ejarque M, Serena C, Duran X, Montori-Grau M, Rodríguez MA, Yanes O, Núñez-Roa C, Roche K, Puthanveetil P, Garrido-Sánchez L, Saez E, Tinahones FJ, Garcia-Roves PM, Gómez-Foix AM, Saltiel AR, Vendrell J, Fernández-Veledo S. Ceperuelo-Mallafré V, et al. Among authors: serena c. Mol Metab. 2015 Oct 16;5(1):5-18. doi: 10.1016/j.molmet.2015.10.001. eCollection 2016 Jan. Mol Metab. 2015. PMID: 26844203 Free PMC article.
Obesity Determines the Immunophenotypic Profile and Functional Characteristics of Human Mesenchymal Stem Cells From Adipose Tissue.
Pachón-Peña G, Serena C, Ejarque M, Petriz J, Duran X, Oliva-Olivera W, Simó R, Tinahones FJ, Fernández-Veledo S, Vendrell J. Pachón-Peña G, et al. Among authors: serena c. Stem Cells Transl Med. 2016 Apr;5(4):464-75. doi: 10.5966/sctm.2015-0161. Epub 2016 Mar 8. Stem Cells Transl Med. 2016. PMID: 26956208 Free PMC article.
Angiopoietin-like protein 8/betatrophin as a new determinant of type 2 diabetes remission after bariatric surgery.
Ejarque M, Borlaug M, Vilarrasa N, Martinez-Perez B, Llauradó G, Megía A, Helland T, Gutierrez C, Serena C, Folkestad O, Nuñez-Roa C, Roche K, Casajoana A, Fradera R, González-Clemente JM, López M, Mohn AC, Nedrebø BG, Nogueiras R, Mellgren G, Fernø J, Fernández-Veledo S, Vendrell J. Ejarque M, et al. Among authors: serena c. Transl Res. 2017 Jun;184:35-44.e4. doi: 10.1016/j.trsl.2017.03.001. Epub 2017 Mar 9. Transl Res. 2017. PMID: 28347650 Clinical Trial.
Survivin, a key player in cancer progression, increases in obesity and protects adipose tissue stem cells from apoptosis.
Ejarque M, Ceperuelo-Mallafré V, Serena C, Pachón G, Núñez-Álvarez Y, Terrón-Puig M, Calvo E, Núñez-Roa C, Oliva-Olivera W, Tinahones FJ, Peinado MA, Vendrell J, Fernández-Veledo S. Ejarque M, et al. Among authors: serena c. Cell Death Dis. 2017 May 18;8(5):e2802. doi: 10.1038/cddis.2017.209. Cell Death Dis. 2017. PMID: 28518147 Free PMC article.
Crohn's Disease Disturbs the Immune Properties of Human Adipose-Derived Stem Cells Related to Inflammasome Activation.
Serena C, Keiran N, Madeira A, Maymó-Masip E, Ejarque M, Terrón-Puig M, Espin E, Martí M, Borruel N, Guarner F, Menacho M, Zorzano A, Millan M, Fernández-Veledo S, Vendrell J. Serena C, et al. Stem Cell Reports. 2017 Oct 10;9(4):1109-1123. doi: 10.1016/j.stemcr.2017.07.014. Epub 2017 Sep 28. Stem Cell Reports. 2017. PMID: 28966116 Free PMC article.
Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota.
Serena C, Ceperuelo-Mallafré V, Keiran N, Queipo-Ortuño MI, Bernal R, Gomez-Huelgas R, Urpi-Sarda M, Sabater M, Pérez-Brocal V, Andrés-Lacueva C, Moya A, Tinahones FJ, Fernández-Real JM, Vendrell J, Fernández-Veledo S. Serena C, et al. ISME J. 2018 Jun;12(7):1642-1657. doi: 10.1038/s41396-018-0068-2. Epub 2018 Feb 12. ISME J. 2018. PMID: 29434314 Free PMC article. Clinical Trial.
Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells.
Ejarque M, Ceperuelo-Mallafré V, Serena C, Maymo-Masip E, Duran X, Díaz-Ramos A, Millan-Scheiding M, Núñez-Álvarez Y, Núñez-Roa C, Gama P, Garcia-Roves PM, Peinado MA, Gimble JM, Zorzano A, Vendrell J, Fernández-Veledo S. Ejarque M, et al. Among authors: serena c. Int J Obes (Lond). 2019 Jun;43(6):1256-1268. doi: 10.1038/s41366-018-0219-6. Epub 2018 Sep 27. Int J Obes (Lond). 2019. PMID: 30262812 Free PMC article.
SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity.
Keiran N, Ceperuelo-Mallafré V, Calvo E, Hernández-Alvarez MI, Ejarque M, Núñez-Roa C, Horrillo D, Maymó-Masip E, Rodríguez MM, Fradera R, de la Rosa JV, Jorba R, Megia A, Zorzano A, Medina-Gómez G, Serena C, Castrillo A, Vendrell J, Fernández-Veledo S. Keiran N, et al. Among authors: serena c. Nat Immunol. 2019 May;20(5):581-592. doi: 10.1038/s41590-019-0372-7. Epub 2019 Apr 8. Nat Immunol. 2019. PMID: 30962591 Free article.
96 results