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Age and sex differences in the effects of the immunosuppressants cyclosporine, sirolimus and everolimus on rat brain metabolism.
Gottschalk S, Cummins CL, Leibfritz D, Christians U, Benet LZ, Serkova NJ. Gottschalk S, et al. Among authors: serkova nj. Neurotoxicology. 2011 Jan;32(1):50-7. doi: 10.1016/j.neuro.2010.10.006. Epub 2010 Nov 12. Neurotoxicology. 2011. PMID: 21075140
Immunosuppressant neurotoxicity in rat brain models: oxidative stress and cellular metabolism.
Klawitter J, Gottschalk S, Hainz C, Leibfritz D, Christians U, Serkova NJ. Klawitter J, et al. Among authors: serkova nj. Chem Res Toxicol. 2010 Mar 15;23(3):608-19. doi: 10.1021/tx900351q. Chem Res Toxicol. 2010. PMID: 20148532 Free PMC article.
Biomarkers for toxicodynamic monitoring of immunosuppressants: NMR-based quantitative metabonomics of the blood.
Serkova NJ, Christians U. Serkova NJ, et al. Ther Drug Monit. 2005 Dec;27(6):733-7. doi: 10.1097/01.ftd.0000179846.30342.65. Ther Drug Monit. 2005. PMID: 16404806
Biochemical mechanisms of cyclosporine neurotoxicity.
Serkova NJ, Christians U, Benet LZ. Serkova NJ, et al. Mol Interv. 2004 Apr;4(2):97-107. doi: 10.1124/mi.4.2.7. Mol Interv. 2004. PMID: 15087483 Review.
Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors.
Christians U, Gottschalk S, Miljus J, Hainz C, Benet LZ, Leibfritz D, Serkova N. Christians U, et al. Among authors: serkova n. Br J Pharmacol. 2004 Oct;143(3):388-96. doi: 10.1038/sj.bjp.0705939. Epub 2004 Aug 31. Br J Pharmacol. 2004. PMID: 15339861 Free PMC article.
Donor pre-treatment with everolimus or cyclosporine does not reduce ischaemia-reperfusion injury in a rat kidney transplant model.
Martinez-Palli G, Hirose R, Liu T, Xu F, Dang K, Feiner J, Serkova NJ, Niemann CU. Martinez-Palli G, et al. Among authors: serkova nj. Nephrol Dial Transplant. 2011 Jun;26(6):1813-20. doi: 10.1093/ndt/gfq646. Epub 2010 Nov 10. Nephrol Dial Transplant. 2011. PMID: 21068143
Comparison of the effects of cyclosporin a on the metabolism of perfused rat brain slices during normoxia and hypoxia.
Serkova N, Donohoe P, Gottschalk S, Hainz C, Niemann CU, Bickler PE, Litt L, Benet LZ, Leibfritz D, Christians U. Serkova N, et al. J Cereb Blood Flow Metab. 2002 Mar;22(3):342-52. doi: 10.1097/00004647-200203000-00012. J Cereb Blood Flow Metab. 2002. PMID: 11891440
Organ-specific response to inhibition of mitochondrial metabolism by cyclosporine in the rat.
Serkova N, Klawitter J, Niemann CU. Serkova N, et al. Transpl Int. 2003 Oct;16(10):748-55. doi: 10.1007/s00147-003-0631-1. Epub 2003 Jun 24. Transpl Int. 2003. PMID: 12827232
Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury.
Fuller TF, Freise CE, Serkova N, Niemann CU, Olson JL, Feng S. Fuller TF, et al. Among authors: serkova n. Transplantation. 2003 Dec 15;76(11):1594-9. doi: 10.1097/01.TP.0000095897.38634.30. Transplantation. 2003. PMID: 14702530
Comparison of the in vitro metabolism of the macrolide immunosuppressants sirolimus and RAD.
Jacobsen W, Serkova N, Hausen B, Morris RE, Benet LZ, Christians U. Jacobsen W, et al. Among authors: serkova n. Transplant Proc. 2001 Feb-Mar;33(1-2):514-5. doi: 10.1016/s0041-1345(00)02116-3. Transplant Proc. 2001. PMID: 11266932 No abstract available.
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