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Relationships between changes in pain severity and other patient-reported outcomes: an analysis in patients with posttraumatic peripheral neuropathic pain.
van Seventer R, Serpell M, Bach FW, Morlion B, Zlateva G, Bushmakin AG, Cappelleri JC, Nimour M. van Seventer R, et al. Health Qual Life Outcomes. 2011 Mar 25;9:17. doi: 10.1186/1477-7525-9-17. Health Qual Life Outcomes. 2011. PMID: 21439051 Free PMC article. Clinical Trial.
5% lidocaine medicated plaster versus pregabalin in post-herpetic neuralgia and diabetic polyneuropathy: an open-label, non-inferiority two-stage RCT study.
Baron R, Mayoral V, Leijon G, Binder A, Steigerwald I, Serpell M. Baron R, et al. Curr Med Res Opin. 2009 Jul;25(7):1663-76. doi: 10.1185/03007990903047880. Curr Med Res Opin. 2009. PMID: 19485723 Clinical Trial.
Efficacy and safety of 5% lidocaine (lignocaine) medicated plaster in comparison with pregabalin in patients with postherpetic neuralgia and diabetic polyneuropathy: interim analysis from an open-label, two-stage adaptive, randomized, controlled trial.
Baron R, Mayoral V, Leijon G, Binder A, Steigerwald I, Serpell M. Baron R, et al. Clin Drug Investig. 2009;29(4):231-41. doi: 10.2165/00044011-200929040-00002. Clin Drug Investig. 2009. PMID: 19301937 Clinical Trial.
The dose was titrated to effect: all patients received 150 mg/day in the first week and 300 mg/day in the second week of treatment. After 1 week at 300 mg/day, the dose of pregabalin was further increased to 600 mg/day in patients with high pain intens …
The dose was titrated to effect: all patients received 150 mg/day in the first week and 300 mg/day in the second week of treat …
A multicentre, open-label, follow-on study to assess the long-term maintenance of effect, tolerance and safety of THC/CBD oromucosal spray in the management of neuropathic pain.
Hoggart B, Ratcliffe S, Ehler E, Simpson KH, Hovorka J, Lejčko J, Taylor L, Lauder H, Serpell M. Hoggart B, et al. J Neurol. 2015 Jan;262(1):27-40. doi: 10.1007/s00415-014-7502-9. Epub 2014 Sep 30. J Neurol. 2015. PMID: 25270679 Clinical Trial.
Pregabalin in the treatment of post-traumatic peripheral neuropathic pain: a randomized double-blind trial.
van Seventer R, Bach FW, Toth CC, Serpell M, Temple J, Murphy TK, Nimour M. van Seventer R, et al. Eur J Neurol. 2010 Aug;17(8):1082-9. doi: 10.1111/j.1468-1331.2010.02979.x. Epub 2010 Mar 4. Eur J Neurol. 2010. PMID: 20236172 Clinical Trial.
METHODS: Patients with a pain score >or=4 (0-10 scale) were randomized and treated with either flexible-dose pregabalin 150-600 mg/day (n = 127) or placebo (n = 127) in an 8-week double-blind treatment period preceded by a 2-week placebo run-in. ...CONCLUSION: Flexible- …
METHODS: Patients with a pain score >or=4 (0-10 scale) were randomized and treated with either flexible-dose pregabalin 150-600 mg
A double-blind, randomized, placebo-controlled, parallel group study of THC/CBD spray in peripheral neuropathic pain treatment.
Serpell M, Ratcliffe S, Hovorka J, Schofield M, Taylor L, Lauder H, Ehler E. Serpell M, et al. Eur J Pain. 2014 Aug;18(7):999-1012. doi: 10.1002/j.1532-2149.2013.00445.x. Epub 2014 Jan 13. Eur J Pain. 2014. PMID: 24420962 Clinical Trial.
Sativex successfully treats neuropathic pain characterised by allodynia: a randomised, double-blind, placebo-controlled clinical trial.
Nurmikko TJ, Serpell MG, Hoggart B, Toomey PJ, Morlion BJ, Haines D. Nurmikko TJ, et al. Among authors: serpell mg. Pain. 2007 Dec 15;133(1-3):210-20. doi: 10.1016/j.pain.2007.08.028. Epub 2007 Nov 7. Pain. 2007. PMID: 17997224 Clinical Trial.
Assessment of Transdermal Buprenorphine Patches for the Treatment of Chronic Pain in a UK Observational Study.
Serpell M, Tripathi S, Scherzinger S, Rojas-Farreras S, Oksche A, Wilson M. Serpell M, et al. Patient. 2016 Feb;9(1):35-46. doi: 10.1007/s40271-015-0151-y. Patient. 2016. PMID: 26547914 Free PMC article. Clinical Trial.
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