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1,602 results
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The tumor suppressor protein p16INK4a.
Serrano M. Serrano M. Exp Cell Res. 1997 Nov 25;237(1):7-13. doi: 10.1006/excr.1997.3824. Exp Cell Res. 1997. PMID: 9417860 Review.
Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.
Pantoja C, Serrano M. Pantoja C, et al. Among authors: serrano m. Oncogene. 1999 Sep 2;18(35):4974-82. doi: 10.1038/sj.onc.1202880. Oncogene. 1999. PMID: 10490832
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a.
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. Serrano M, et al. Cell. 1997 Mar 7;88(5):593-602. doi: 10.1016/s0092-8674(00)81902-9. Cell. 1997. PMID: 9054499
Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas.
Malumbres M, Pérez de Castro I, Santos J, Meléndez B, Mangues R, Serrano M, Pellicer A, Fernández-Piqueras J. Malumbres M, et al. Among authors: serrano m. Oncogene. 1997 Mar 20;14(11):1361-70. doi: 10.1038/sj.onc.1200969. Oncogene. 1997. PMID: 9178896
Role of the INK4a locus in tumor suppression and cell mortality.
Serrano M, Lee H, Chin L, Cordon-Cardo C, Beach D, DePinho RA. Serrano M, et al. Cell. 1996 Apr 5;85(1):27-37. doi: 10.1016/s0092-8674(00)81079-x. Cell. 1996. PMID: 8620534
Association of rat p15INK4B/p16INK4 deletions with monosomy 5 in kidney epithelial cell lines but not primary renal tumors.
Knapek DF, Serrano M, Beach D, Trono D, Walker CL. Knapek DF, et al. Among authors: serrano m. Cancer Res. 1995 Apr 15;55(8):1607-12. Cancer Res. 1995. PMID: 7712460
Analysis of p16INK4a and its interaction with CDK4.
Yang R, Serrano M, Slater J, Leung E, Koeffler HP. Yang R, et al. Among authors: serrano m. Biochem Biophys Res Commun. 1996 Jan 5;218(1):254-9. doi: 10.1006/bbrc.1996.0045. Biochem Biophys Res Commun. 1996. PMID: 8573142
Mutational effects on the p16INK4a tumor suppressor protein.
Yang R, Gombart AF, Serrano M, Koeffler HP. Yang R, et al. Among authors: serrano m. Cancer Res. 1995 Jun 15;55(12):2503-6. Cancer Res. 1995. PMID: 7780957
Cloning and characterization of murine p16INK4a and p15INK4b genes.
Quelle DE, Ashmun RA, Hannon GJ, Rehberger PA, Trono D, Richter KH, Walker C, Beach D, Sherr CJ, Serrano M. Quelle DE, et al. Among authors: serrano m. Oncogene. 1995 Aug 17;11(4):635-45. Oncogene. 1995. PMID: 7651726
A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma.
Wölfel T, Hauer M, Schneider J, Serrano M, Wölfel C, Klehmann-Hieb E, De Plaen E, Hankeln T, Meyer zum Büschenfelde KH, Beach D. Wölfel T, et al. Among authors: serrano m. Science. 1995 Sep 1;269(5228):1281-4. doi: 10.1126/science.7652577. Science. 1995. PMID: 7652577
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