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Treatment-emergent sexual dysfunction related to antidepressants: a meta-analysis.
Serretti A, Chiesa A. Serretti A, et al. J Clin Psychopharmacol. 2009 Jun;29(3):259-66. doi: 10.1097/JCP.0b013e3181a5233f. J Clin Psychopharmacol. 2009. PMID: 19440080 Review.
DISCUSSION: Treatment-emergent SD caused by antidepressants is a considerable issue with a large variation across compounds. ...However, treatment-emergent SD is a frequent adverse effect that should be considered in clinical activity for the choice of the pr …
DISCUSSION: Treatment-emergent SD caused by antidepressants is a considerable issue with a large variation across compounds. . …
Effects of fluoxetine at antidepressant doses on short-term outcome of detoxified alcoholics.
Janiri L, Gobbi G, Mannelli P, Pozzi G, Serretti A, Tempesta E. Janiri L, et al. Among authors: serretti a. Int Clin Psychopharmacol. 1996 Jun;11(2):109-17. Int Clin Psychopharmacol. 1996. PMID: 8803648 Clinical Trial.
Compulsivity in alcohol-dependent patients is a frequent cause of early relapse in the post-detoxification period. The present study is a 2-month trial on detoxified alcoholics undergoing a double-blind placebo-controlled treatment with fluoxetine (20 mg/day) …
Compulsivity in alcohol-dependent patients is a frequent cause of early relapse in the post-detoxification period. The present study …
Patterns of symptom improvement during antidepressant treatment of delusional depression.
Serretti A, Lattuada E, Zanardi R, Franchini L, Smeraldi E. Serretti A, et al. Psychiatry Res. 2000 May 15;94(2):185-90. doi: 10.1016/s0165-1781(00)00139-6. Psychiatry Res. 2000. PMID: 10808044
HAMD depressive symptom clusters decreased in a parallel manner from baseline to the end of the 6-week trial. The RRM analysis revealed no significant difference between HAMD clusters and the time course of the total HAMD score during treatment. Our data indicate that ther …
HAMD depressive symptom clusters decreased in a parallel manner from baseline to the end of the 6-week trial. The RRM analysis reveal …
SSRIs antidepressant activity is influenced by G beta 3 variants.
Serretti A, Lorenzi C, Cusin C, Zanardi R, Lattuada E, Rossini D, Lilli R, Pirovano A, Catalano M, Smeraldi E. Serretti A, et al. Eur Neuropsychopharmacol. 2003 Mar;13(2):117-22. doi: 10.1016/s0924-977x(02)00154-2. Eur Neuropsychopharmacol. 2003. PMID: 12650956 Clinical Trial.
The aim of the present study was to test a possible effect of the G-protein beta3-subunit (Gbeta3) C825T gene variant on the antidepressant activity of selective serotonin reuptake inhibitors (SSRIs) in a sample of major and bipolar depressives, with or without psyc …
The aim of the present study was to test a possible effect of the G-protein beta3-subunit (Gbeta3) C825T gene variant on the antidepr …
Clinical features of antidepressant associated manic and hypomanic switches in bipolar disorder.
Serretti A, Artioli P, Zanardi R, Rossini D. Serretti A, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2003 Aug;27(5):751-7. doi: 10.1016/S0278-5846(03)00104-0. Prog Neuropsychopharmacol Biol Psychiatry. 2003. PMID: 12921905
They were compared with a sex, age (+/-5 years), and ethnicity-matched group of 247 subjects, randomly selected from our pool of bipolar subjects who have never had manic switches. ...Maintenance with mood stabilizers appears to be a strong protective factor; in fac …
They were compared with a sex, age (+/-5 years), and ethnicity-matched group of 247 subjects, randomly selected from our pool of bipo …
Comparison of response to fluvoxamine in nondemented elderly compared to younger patients affected by major depression.
Zanardi R, Cusin C, Rossini D, De Ronchi D, Serretti A. Zanardi R, et al. Among authors: serretti a. J Clin Psychopharmacol. 2003 Dec;23(6):535-9. doi: 10.1097/01.jcp.0000095344.32154.d3. J Clin Psychopharmacol. 2003. PMID: 14624182
In this study, we analyzed antidepressant response in 528 nondemented consecutive inpatients affected by a major depressive episode. The sample was divided based on a cut-off of 60 years (< or = 60 n = 354; mean age 46.6 +/- 10.4 years; > 60 n = 174; mean age …
In this study, we analyzed antidepressant response in 528 nondemented consecutive inpatients affected by a major depressive episode. …
Paroxetine in the treatment of depressed patients with haematological malignancy: an open-label study.
Pae CU, Kim YJ, Won WY, Kim HJ, Lee S, Lee CU, Lee SJ, Kim DW, Lee C, Min WS, Kim CC, Paik IH, Serretti A. Pae CU, et al. Among authors: serretti a. Hum Psychopharmacol. 2004 Jan;19(1):25-9. doi: 10.1002/hup.541. Hum Psychopharmacol. 2004. PMID: 14716708 Clinical Trial.
Scores on the HAM-D17, MADRS and CGI-s (last observation carried forward, LOCF) at baseline were significantly reduced with a mean reduction of 30.5%, 32.8% and 39.1%, respectively, after 8 weeks treatment with paroxetine. CONCLUSION: In this preliminary study, paroxetine …
Scores on the HAM-D17, MADRS and CGI-s (last observation carried forward, LOCF) at baseline were significantly reduced with a mean re …
From molecular biology to pharmacogenetics: a review of the literature on antidepressant treatment and suggestions of possible candidate genes.
Serretti A, Artioli P. Serretti A, et al. Psychopharmacology (Berl). 2004 Aug;174(4):490-503. doi: 10.1007/s00213-004-1822-x. Epub 2004 Mar 2. Psychopharmacology (Berl). 2004. PMID: 14997279 Review.
Pharmacogenetic studies in mood disorders are raising increasing interest, after the first findings of a significant association between antidepressant response and a functional polymorphism in the upstream regulatory region of the serotonin transporter gene (SERTPR …
Pharmacogenetic studies in mood disorders are raising increasing interest, after the first findings of a significant association betw …
The pharmacogenomics of selective serotonin reuptake inhibitors.
Serretti A, Artioli P. Serretti A, et al. Pharmacogenomics J. 2004;4(4):233-44. doi: 10.1038/sj.tpj.6500250. Pharmacogenomics J. 2004. PMID: 15111987 Review.
The introduction of selective serotonin (5-HT) reuptake inhibitors (SSRIs) has significantly improved the pharmacological treatment of a range of psychiatric disorders. ...The hope is that the identification of these genetic components will eventually facilitate the develo …
The introduction of selective serotonin (5-HT) reuptake inhibitors (SSRIs) has significantly improved the pharmacological treatment of a
Further evidence for a possible association between serotonin transporter gene and lithium prophylaxis in mood disorders.
Serretti A, Malitas PN, Mandelli L, Lorenzi C, Ploia C, Alevizos B, Nikolaou C, Boufidou F, Christodoulou GN, Smeraldi E. Serretti A, et al. Pharmacogenomics J. 2004;4(4):267-73. doi: 10.1038/sj.tpj.6500252. Pharmacogenomics J. 2004. PMID: 15111989
SERTPR variants were associated with lithium outcome among those subjects who had few manic episodes before lithium treatment and, as a trend, among subjects who received a high daily dose of lithium (> or =1200 mg/die). ...The present study confirmed our previou …
SERTPR variants were associated with lithium outcome among those subjects who had few manic episodes before lithium treatment and, as a
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