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Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes.
Solvay M, Holfelder P, Klaessens S, Pilotte L, Stroobant V, Lamy J, Naulaerts S, Spillier Q, Frédérick R, De Plaen E, Sers C, Opitz CA, Van den Eynde BJ, Zhu J. Solvay M, et al. Among authors: sers c. J Immunother Cancer. 2023 Jun;11(6):e006728. doi: 10.1136/jitc-2023-006728. J Immunother Cancer. 2023. PMID: 37344101 Free PMC article.
A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts.
Blüthgen N, Legewie S, Kielbasa SM, Schramme A, Tchernitsa O, Keil J, Solf A, Vingron M, Schäfer R, Herzel H, Sers C. Blüthgen N, et al. Among authors: sers c. FEBS J. 2009 Feb;276(4):1024-35. doi: 10.1111/j.1742-4658.2008.06846.x. Epub 2009 Jan 12. FEBS J. 2009. PMID: 19154344 Free article.
Therapeutic potential of CAMPATH-1H in skeletal tumours.
Fritsche-Guenther R, Gruetzkau A, Noske A, Melcher I, Schaser KD, Schlag PM, Kasper HU, Krenn V, Sers C. Fritsche-Guenther R, et al. Among authors: sers c. Histopathology. 2010 Dec;57(6):851-61. doi: 10.1111/j.1365-2559.2010.03722.x. Histopathology. 2010. PMID: 21166699
Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.
Jürchott K, Kuban RJ, Krech T, Blüthgen N, Stein U, Walther W, Friese C, Kiełbasa SM, Ungethüm U, Lund P, Knösel T, Kemmner W, Morkel M, Fritzmann J, Schlag PM, Birchmeier W, Krueger T, Sperling S, Sers C, Royer HD, Herzel H, Schäfer R. Jürchott K, et al. Among authors: sers c. PLoS Genet. 2010 Dec 2;6(12):e1001231. doi: 10.1371/journal.pgen.1001231. PLoS Genet. 2010. PMID: 21170361 Free PMC article.
125 results