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Year Number of Results
1968 1
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35 results

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Page 1
DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies.
Schultz KAP, Williams GM, Kamihara J, Stewart DR, Harris AK, Bauer AJ, Turner J, Shah R, Schneider K, Schneider KW, Carr AG, Harney LA, Baldinger S, Frazier AL, Orbach D, Schneider DT, Malkin D, Dehner LP, Messinger YH, Hill DA. Schultz KAP, et al. Clin Cancer Res. 2018 May 15;24(10):2251-2261. doi: 10.1158/1078-0432.CCR-17-3089. Epub 2018 Jan 17. Clin Cancer Res. 2018. PMID: 29343557 Free PMC article. Review.
In addition to conferring increased cancer risks for pleuropulmonary blastoma (PPB) and ovarian sex cord-stromal tumors, particularly Sertoli-Leydig cell tumor, individuals with pathogenic germline DICER1 variants may also develop lung cysts, cystic nephroma, renal …
In addition to conferring increased cancer risks for pleuropulmonary blastoma (PPB) and ovarian sex cord-stromal tumors, particularly Ser
Klinefelter syndrome.
Wikström AM, Dunkel L. Wikström AM, et al. Best Pract Res Clin Endocrinol Metab. 2011 Apr;25(2):239-50. doi: 10.1016/j.beem.2010.09.006. Best Pract Res Clin Endocrinol Metab. 2011. PMID: 21397196 Review.
Testicular biopsies of prepubertal KS boys have shown preservation of seminiferous tubules with reduced numbers of germ cells, but Sertoli and Leydig cells have appeared normal. The testes in the adult KS male are characterized by extensive fibrosis and hyali …
Testicular biopsies of prepubertal KS boys have shown preservation of seminiferous tubules with reduced numbers of germ cells, but …
Ovarian spindle cell lesions: a review with emphasis on recent developments and differential diagnosis.
Irving JA, McCluggage WG. Irving JA, et al. Adv Anat Pathol. 2007 Sep;14(5):305-19. doi: 10.1097/PAP.0b013e3180ca8a5b. Adv Anat Pathol. 2007. PMID: 17717430 Review.
This review discusses the main differential diagnoses of an ovarian spindle cell lesion, especially concentrating on the recent literature. The majority of ovarian spindle cell lesions fall into the broad category of fibromatous neoplasms whereas others in the sex c …
This review discusses the main differential diagnoses of an ovarian spindle cell lesion, especially concentrating on the recent liter …
Roles of connexins in testis development and spermatogenesis.
Kidder GM, Cyr DG. Kidder GM, et al. Semin Cell Dev Biol. 2016 Feb;50:22-30. doi: 10.1016/j.semcdb.2015.12.019. Epub 2016 Jan 11. Semin Cell Dev Biol. 2016. PMID: 26780117 Review.
Loss of Cx43 in the fetus results in a decreased number of germ cells, while the loss of Cx43 in the adult Sertoli cells results in complete inhibition of spermatogenesis. ...In contrast, loss of Cx43 from Sertoli cells results in Leydig cell
Loss of Cx43 in the fetus results in a decreased number of germ cells, while the loss of Cx43 in the adult Sertoli cells
What Does AMH Tell Us in Pediatric Disorders of Sex Development?
Josso N, Rey RA. Josso N, et al. Front Endocrinol (Lausanne). 2020 Sep 8;11:619. doi: 10.3389/fendo.2020.00619. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 33013698 Free PMC article. Review.
Anti-Mullerian hormone (AMH), a glycoprotein hormone produced in large amounts by immature testicular Sertoli cells, may be an extremely helpful parameter. In undervirilized 46,XY DSD, AMH is low in gonadal dysgenesis while it is normal or high in androgen insensiti …
Anti-Mullerian hormone (AMH), a glycoprotein hormone produced in large amounts by immature testicular Sertoli cells, may be an …
The relationship between testicular tumour characteristics and azoospermia: a systematic review.
Pang KH, Osman NI, Muneer A, Alnajjar HM. Pang KH, et al. Int J Impot Res. 2022 Sep;34(6):543-551. doi: 10.1038/s41443-021-00492-x. Epub 2021 Nov 6. Int J Impot Res. 2022. PMID: 34743192 Review.
Bilateral TT (12.3% vs 2.9% in non-azoospermia), non-seminoma germ cell tumours (6.4% vs 1.9%), germ cell neoplasia in-situ (GCNIS) (11.1% vs 1.2%), stage 2-3 disease (22.2% vs 0%), Sertoli Cell only (SCO) on biopsy (60% vs 37.5%) and a history of unde …
Bilateral TT (12.3% vs 2.9% in non-azoospermia), non-seminoma germ cell tumours (6.4% vs 1.9%), germ cell neoplasia in-situ (G …
Testicular function in Klinefelter syndrome.
Wikström AM, Dunkel L. Wikström AM, et al. Horm Res. 2008;69(6):317-26. doi: 10.1159/000117387. Epub 2008 Mar 17. Horm Res. 2008. PMID: 18504390 Free article. Review.
Testicular biopsies of prepubertal KS boys have shown preservation of seminiferous tubules with reduced numbers of germ cells, but Sertoli and Leydig cells have appeared normal. The testes in the adult KS male are, however, characterized by extensive fibrosis …
Testicular biopsies of prepubertal KS boys have shown preservation of seminiferous tubules with reduced numbers of germ cells, but …
Sertoli-Leydig cell tumor presenting hyperestrogenism in a postmenopausal woman: a case report and review of the literature.
Guo L, Yang X, Zhu H, Qiu W, Shi X, Huang B, Duan T. Guo L, et al. Taiwan J Obstet Gynecol. 2012 Dec;51(4):620-4. doi: 10.1016/j.tjog.2012.09.019. Taiwan J Obstet Gynecol. 2012. PMID: 23276568 Free article. Review.
OBJECTIVE: Sertoli-Leydig cell tumor (SLCT) accounts for <0.5% of all ovarian tumors, which is unusual in postmenopausal women. ...The tumor was positive for inhibin-alpha, pancytokeratin, and p53 and in isolated tumor cells, positive for Ki-67. CONCLUSION …
OBJECTIVE: Sertoli-Leydig cell tumor (SLCT) accounts for <0.5% of all ovarian tumors, which is unusual in postmenopausal wo …
Granulosa cell tumor of the adult testis: a clinicopathologic study of seven cases and a review of the literature.
Jimenez-Quintero LP, Ro JY, Zavala-Pompa A, Amin MB, Tetu B, Ordoñez NG, Ayala AG. Jimenez-Quintero LP, et al. Hum Pathol. 1993 Oct;24(10):1120-5. doi: 10.1016/0046-8177(93)90193-k. Hum Pathol. 1993. PMID: 8406422 Review.
Call-Exner bodies were present in three tumors and two tumors had a focal spindle-cell component. In one case the surrounding testicular parenchyma showed Leydig's cell hyperplasia and a Sertoli cell nodule. The tumor cells revealed stron …
Call-Exner bodies were present in three tumors and two tumors had a focal spindle-cell component. In one case the surrounding testicu …
Sex cord-stromal and steroid cell tumors of the ovary.
Outwater EK, Wagner BJ, Mannion C, McLarney JK, Kim B. Outwater EK, et al. Radiographics. 1998 Nov-Dec;18(6):1523-46. doi: 10.1148/radiographics.18.6.9821198. Radiographics. 1998. PMID: 9821198 Review.
Gonadal cell types that derive from the coelomic epithelium (sex cords) or mesenchymal cells of the embryonic gonads include granulosa cells, theca cells, fibroblasts, Leydig cells, and Sertoli cells. ...The more common types are g …
Gonadal cell types that derive from the coelomic epithelium (sex cords) or mesenchymal cells of the embryonic gonads include g …
35 results