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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1918 1
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1953 3
1954 1
1955 2
1956 1
1957 1
1958 9
1959 3
1961 2
1962 1
1963 3
1964 7
1965 8
1966 23
1967 13
1968 26
1969 34
1970 45
1971 40
1972 40
1973 46
1974 39
1975 56
1976 62
1977 65
1978 59
1979 50
1980 84
1981 86
1982 76
1983 94
1984 124
1985 95
1986 100
1987 90
1988 73
1989 95
1990 98
1991 81
1992 86
1993 87
1994 82
1995 82
1996 97
1997 93
1998 92
1999 106
2000 108
2001 109
2002 108
2003 100
2004 124
2005 132
2006 131
2007 128
2008 124
2009 117
2010 156
2011 142
2012 180
2013 211
2014 182
2015 194
2016 215
2017 217
2018 219
2019 206
2020 255
2021 213
2022 231
2023 206
2024 202
2025 10

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6,195 results

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Page 1
Ketone bodies in cell physiology and cancer.
Giuliani G, Longo VD. Giuliani G, et al. Am J Physiol Cell Physiol. 2024 Mar 1;326(3):C948-C963. doi: 10.1152/ajpcell.00441.2023. Epub 2024 Jan 8. Am J Physiol Cell Physiol. 2024. PMID: 38189128 Review.
Ketogenic diets (KDs), fasting, or prolonged physical activity elevate serum ketone bodies (KBs) levels, providing an alternative fuel source for the brain and other organs. ...
Ketogenic diets (KDs), fasting, or prolonged physical activity elevate serum ketone bodies (KBs) levels, providing an alternat …
Ketone monoester ingestion increases postexercise serum erythropoietin concentrations in healthy men.
Evans E, Walhin JP, Hengist A, Betts JA, Dearlove DJ, Gonzalez JT. Evans E, et al. Am J Physiol Endocrinol Metab. 2023 Jan 1;324(1):E56-E61. doi: 10.1152/ajpendo.00264.2022. Epub 2022 Nov 30. Am J Physiol Endocrinol Metab. 2023. PMID: 36449571 Free PMC article.

Peak serum EPO concentrations were higher with KETONE (means SD: 9.0 2.3 IU.L(-1)) compared with CONTROL (7.5 1.5 IU.L(-1), P < 0.01). ...We demonstrated that ingestion of a ketone monoester postexercise increased serum erythropoietin concentrations

…
Peak serum EPO concentrations were higher with KETONE (means SD: 9.0 2.3 IU.L(-1)) compared with CONTROL (7.5 1.5 IU.L(-1), P …
Elevated serum beta-hydroxybutyrate, a circulating ketone metabolite, accelerates colorectal cancer proliferation and metastasis via ACAT1.
Mao T, Qin F, Zhang M, Li J, Li J, Lai M. Mao T, et al. Oncogene. 2023 Jun;42(23):1889-1899. doi: 10.1038/s41388-023-02700-y. Epub 2023 Apr 25. Oncogene. 2023. PMID: 37185457
Here, we first confirm the increased level of beta-hydroxybutyrate by targeted metabolomic analysis using an independent cohort of 400 serum samples by UPLC-QQQ-MS/MS analysis. Using appropriate cell and animal models, we find that treatment with pathological levels of bet …
Here, we first confirm the increased level of beta-hydroxybutyrate by targeted metabolomic analysis using an independent cohort of 400 se …
Euglycemic diabetic ketoacidosis in the era of SGLT-2 inhibitors.
Chow E, Clement S, Garg R. Chow E, et al. BMJ Open Diabetes Res Care. 2023 Oct;11(5):e003666. doi: 10.1136/bmjdrc-2023-003666. BMJ Open Diabetes Res Care. 2023. PMID: 37797963 Free PMC article. Review.
The paper presents a classification system for the severity of EDKA, categorizing it into mild, moderate, and severe based on serum pH and bicarbonate levels. Another classification system is proposed to define stages of EDKA based on anion gap and ketones at the ti …
The paper presents a classification system for the severity of EDKA, categorizing it into mild, moderate, and severe based on serum p …
Serum Ketone Levels May Correspond with Preoperative Body Weight Loss in Patients Undergoing Elective Surgery: A Single-Center, Prospective, Observational Feasibility Study.
Kutnik P, Borys M, Buszewicz G, Piwowarczyk P, Osak M, Teresiński G, Czuczwar M. Kutnik P, et al. Int J Environ Res Public Health. 2022 May 27;19(11):6573. doi: 10.3390/ijerph19116573. Int J Environ Res Public Health. 2022. PMID: 35682159 Free PMC article.
Previous medical history could be unavailable in unconscious or demented patients. This study aimed to assess the ketone bodies serum levels in patients undergoing elective surgeries and to determine the possible correlation between ketone bodies serum …
Previous medical history could be unavailable in unconscious or demented patients. This study aimed to assess the ketone bodies se …
Downregulation of HDAC9 by the ketone metabolite beta-hydroxybutyrate suppresses vascular calcification.
Lan Z, Chen A, Li L, Ye Y, Liang Q, Dong Q, Wang S, Fu M, Li Y, Liu X, Zhu Z, Ou JS, Qiu X, Lu L, Yan J. Lan Z, et al. J Pathol. 2022 Nov;258(3):213-226. doi: 10.1002/path.5992. Epub 2022 Aug 31. J Pathol. 2022. PMID: 35894849
However, an effective therapy for vascular calcification is still lacking. The ketone body beta-hydroxybutyrate (BHB) has been demonstrated to have health-promoting effects including anti-inflammation and cardiovascular protective effects. ...Of note, compared with CKD pat …
However, an effective therapy for vascular calcification is still lacking. The ketone body beta-hydroxybutyrate (BHB) has been demons …
Pioglitazone reduces serum ketone bodies in sodium-glucose cotransporter-2 inhibitor-treated non-obese type 2 diabetes: A single-centre, randomized, crossover trial.
Yang M, Yue H, Xu Q, Shao S, Chen Y. Yang M, et al. Diabetes Obes Metab. 2024 Aug;26(8):3137-3146. doi: 10.1111/dom.15641. Epub 2024 May 3. Diabetes Obes Metab. 2024. PMID: 38699792 Clinical Trial.
The secondary outcomes were deltachanges in serum acetoacetate and acetone, the rate of conversion into urinary ketones, and deltachanges in factors related to SGLT2 inhibitor-induced ketone body production including non-esterified fatty acids (NEFAs), glucag …
The secondary outcomes were deltachanges in serum acetoacetate and acetone, the rate of conversion into urinary ketones, and d …
Comparison of Serum Ketone Levels and Cardiometabolic Efficacy of Dapagliflozin versus Sitagliptin among Insulin-Treated Chinese Patients with Type 2 Diabetes Mellitus.
Lee CH, Wu MZ, Lui DT, Chan DS, Fong CH, Shiu SW, Wong Y, Lee AC, Lam JK, Woo YC, Lam KS, Yiu KK, Tan KC. Lee CH, et al. Diabetes Metab J. 2022 Nov;46(6):843-854. doi: 10.4093/dmj.2021.0319. Epub 2022 Apr 28. Diabetes Metab J. 2022. PMID: 35483674 Free PMC article. Clinical Trial.
BACKGROUND: Insulin-treated patients with long duration of type 2 diabetes mellitus (T2DM) are at increased risk of ketoacidosis related to sodium-glucose co-transporter 2 inhibitor (SGLT2i). The extent of circulating ketone elevation in these patients remains unknown. We …
BACKGROUND: Insulin-treated patients with long duration of type 2 diabetes mellitus (T2DM) are at increased risk of ketoacidosis related to …
Utility of serum ketone levels for assessment of myocardial glucose suppression for (18)F-fluorodeoxyglucose PET in patients referred for evaluation of endocarditis.
Madamanchi C, Weinberg RL, Murthy VL. Madamanchi C, et al. J Nucl Cardiol. 2023 Jun;30(3):928-937. doi: 10.1007/s12350-023-03209-3. Epub 2023 Feb 23. J Nucl Cardiol. 2023. PMID: 36823484
It requires myocardial glucose utilization (MGU) suppression to avoid false positives, which occur in up to 20% of patients. Serum beta-hydroxybutyrate (BHB) levels may help identify incomplete suppression of MGU. ...BHB measured ~ 4 hours prior to (18)F-FDG injection perf …
It requires myocardial glucose utilization (MGU) suppression to avoid false positives, which occur in up to 20% of patients. Serum be …
Association between Edinburgh Postnatal Depression Scale and Serum Levels of Ketone Bodies and Vitamin D, Thyroid Function, and Iron Metabolism.
Noshiro K, Umazume T, Inubashiri M, Tamura M, Hosaka M, Watari H. Noshiro K, et al. Nutrients. 2023 Feb 2;15(3):768. doi: 10.3390/nu15030768. Nutrients. 2023. PMID: 36771476 Free PMC article.
We defined an EPDS score of 9 as being positive for postpartum depression, and serum ketone levels were found to be higher in the group with an EPDS score of 9 during the second trimester; however, there were no other significant findings. We may be able to predict …
We defined an EPDS score of 9 as being positive for postpartum depression, and serum ketone levels were found to be higher in …
6,195 results