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A Randomized, Double-Blinded, Placebo-Controlled, Phase 1 Study of a Replication-Defective Herpes Simplex Virus (HSV) Type 2 Vaccine, HSV529, in Adults With or Without HSV Infection.
Dropulic LK, Oestreich MC, Pietz HL, Laing KJ, Hunsberger S, Lumbard K, Garabedian D, Turk SP, Chen A, Hornung RL, Seshadri C, Smith MT, Hosken NA, Phogat S, Chang LJ, Koelle DM, Wang K, Cohen JI. Dropulic LK, et al. Among authors: seshadri c. J Infect Dis. 2019 Aug 9;220(6):990-1000. doi: 10.1093/infdis/jiz225. J Infect Dis. 2019. PMID: 31058977 Free PMC article. Clinical Trial.
Toll-like receptor chaperone HSP90B1 and the immune response to Mycobacteria.
Graustein AD, Misch EA, Musvosvi M, Shey M, Shah JA, Seshadri C, Ajuogu A, Bowman K, Mulenga H, Veldsman A, Hanekom WA, Hatherill M, Scriba TJ, Hawn TR. Graustein AD, et al. Among authors: seshadri c. PLoS One. 2018 Dec 14;13(12):e0208940. doi: 10.1371/journal.pone.0208940. eCollection 2018. PLoS One. 2018. PMID: 30550567 Free PMC article.
CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis.
James CA, Yu KKQ, Gilleron M, Prandi J, Yedulla VR, Moleda ZZ, Diamanti E, Khan M, Aggarwal VK, Reijneveld JF, Reinink P, Lenz S, Emerson RO, Scriba TJ, Souter MNT, Godfrey DI, Pellicci DG, Moody DB, Minnaard AJ, Seshadri C, Van Rhijn I. James CA, et al. Among authors: seshadri c. Cell Chem Biol. 2018 Apr 19;25(4):392-402.e14. doi: 10.1016/j.chembiol.2018.01.006. Epub 2018 Feb 1. Cell Chem Biol. 2018. PMID: 29398561 Free PMC article.
CD1b tetramers bind αβ T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans.
Kasmar AG, van Rhijn I, Cheng TY, Turner M, Seshadri C, Schiefner A, Kalathur RC, Annand JW, de Jong A, Shires J, Leon L, Brenner M, Wilson IA, Altman JD, Moody DB. Kasmar AG, et al. Among authors: seshadri c. J Exp Med. 2011 Aug 29;208(9):1741-7. doi: 10.1084/jem.20110665. Epub 2011 Aug 1. J Exp Med. 2011. PMID: 21807869 Free PMC article.
IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure.
Lu LL, Smith MT, Yu KKQ, Luedemann C, Suscovich TJ, Grace PS, Cain A, Yu WH, McKitrick TR, Lauffenburger D, Cummings RD, Mayanja-Kizza H, Hawn TR, Boom WH, Stein CM, Fortune SM, Seshadri C, Alter G. Lu LL, et al. Among authors: seshadri c. Nat Med. 2019 Jun;25(6):977-987. doi: 10.1038/s41591-019-0441-3. Epub 2019 May 20. Nat Med. 2019. PMID: 31110348 Free PMC article.
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