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Molecular mechanism of insulin resistance in type 2 diabetes mellitus: role of the insulin receptor variant forms.
Sesti G, Federici M, Lauro D, Sbraccia P, Lauro R. Sesti G, et al. Diabetes Metab Res Rev. 2001 Sep-Oct;17(5):363-73. doi: 10.1002/dmrr.225. Diabetes Metab Res Rev. 2001. PMID: 11747141 Review.
Evidence that two naturally occurring human insulin receptor alpha-subunit variants are immunologically distinct.
Sesti G, Marini MA, Montemurro A, Condorelli L, Borboni P, Haring HU, Ullrich A, Goldfine ID, De Pirro R, Lauro R. Sesti G, et al. Diabetes. 1992 Jan;41(1):6-11. doi: 10.2337/diab.41.1.6. Diabetes. 1992. PMID: 1727740
Altered expression of the two naturally occurring human insulin receptor variants in isolated adipocytes of non-insulin-dependent diabetes mellitus patients.
Sesti G, Marini MA, Tullio AN, Montemurro A, Borboni P, Fusco A, Accili D, Lauro R. Sesti G, et al. Biochem Biophys Res Commun. 1991 Dec 31;181(3):1419-24. doi: 10.1016/0006-291x(91)92097-4. Biochem Biophys Res Commun. 1991. PMID: 1764093
Direct modulation of insulin receptor protein tyrosine kinase by vanadate and anti-insulin receptor monoclonal antibodies.
Gherzi R, Caratti C, Andraghetti G, Bertolini S, Montemurro A, Sesti G, Cordera R. Gherzi R, et al. Among authors: sesti g. Biochem Biophys Res Commun. 1988 May 16;152(3):1474-80. doi: 10.1016/s0006-291x(88)80452-2. Biochem Biophys Res Commun. 1988. PMID: 2837189
Insulin receptor tyrosine-kinase activity is altered in both muscle and adipose tissue from non-obese normoglycaemic insulin-resistant subjects.
Grasso G, Frittitta L, Anello M, Russo P, Sesti G, Trischitta V. Grasso G, et al. Among authors: sesti g. Diabetologia. 1995 Jan;38(1):55-61. doi: 10.1007/BF02369353. Diabetologia. 1995. PMID: 7744230
Peptide-based radioimmunoassay for the two isoforms of the human insulin receptor.
Sesti G, D'Alfonso R, Vargas Punti MD, Frittitta L, Trischitta V, Liu YY, Borboni P, Longhi R, Montemurro A, Lauro R. Sesti G, et al. Diabetologia. 1995 Apr;38(4):445-53. doi: 10.1007/BF00410282. Diabetologia. 1995. PMID: 7796985
Tissue-specific expression of two alternatively spliced isoforms of the human insulin receptor protein.
Sesti G, Tullio AN, D'Alfonso R, Napolitano ML, Marini MA, Borboni P, Longhi R, Albonici L, Fusco A, Aglianò AM, et al. Sesti G, et al. Acta Diabetol. 1994 Jun;31(2):59-65. doi: 10.1007/BF00570536. Acta Diabetol. 1994. PMID: 7949223
Variant sequences of insulin receptor substrate-1 in patients with noninsulin-dependent diabetes mellitus.
Imai Y, Fusco A, Suzuki Y, Lesniak MA, D'Alfonso R, Sesti G, Bertoli A, Lauro R, Accili D, Taylor SI. Imai Y, et al. Among authors: sesti g. J Clin Endocrinol Metab. 1994 Dec;79(6):1655-8. doi: 10.1210/jcem.79.6.7989470. J Clin Endocrinol Metab. 1994. PMID: 7989470
Altered pattern of insulin receptor isotypes in skeletal muscle membranes of type 2 (non-insulin-dependent) diabetic subjects.
Kellerer M, Sesti G, Seffer E, Obermaier-Kusser B, Pongratz DE, Mosthaf L, Häring HU. Kellerer M, et al. Among authors: sesti g. Diabetologia. 1993 Jul;36(7):628-32. doi: 10.1007/BF00404072. Diabetologia. 1993. PMID: 8359580
Delayed intracellular dissociation of the insulin-receptor complex impairs receptor recycling and insulin processing in cultured Epstein-Barr virus-transformed lymphocytes from insulin-resistant subjects.
Sesti G, D'Alfonso R, Vargas Punti MD, Tullio AN, Liu YY, Federici M, Borboni P, Marini MA, Lauro R, Fusco A. Sesti G, et al. Diabetologia. 1996 Mar;39(3):289-95. doi: 10.1007/BF00418344. Diabetologia. 1996. PMID: 8721774
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