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A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
Shishodia S, Sethi G, Konopleva M, Andreeff M, Aggarwal BB. Shishodia S, et al. Among authors: sethi g. Clin Cancer Res. 2006 Mar 15;12(6):1828-38. doi: 10.1158/1078-0432.CCR-05-2044. Clin Cancer Res. 2006. PMID: 16551868
Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells.
Bhardwaj A, Sethi G, Vadhan-Raj S, Bueso-Ramos C, Takada Y, Gaur U, Nair AS, Shishodia S, Aggarwal BB. Bhardwaj A, et al. Among authors: sethi g. Blood. 2007 Mar 15;109(6):2293-302. doi: 10.1182/blood-2006-02-003988. Epub 2006 Dec 12. Blood. 2007. PMID: 17164350
768 results