Sethi G - Search Results

1

Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.

Ramachandran L, Manu KA, Shanmugam MK, Li F, Siveen KS, Vali S, Kapoor S, Abbasi T, Surana R, Smoot DT, Ashktorab H, Tan P, Ahn KS, Yap CW, Kumar AP, Sethi G. Ramachandran L, et al. Among authors: sethi g. J Biol Chem. 2012 Nov 2;287(45):38028-40. doi: 10.1074/jbc.M112.388702. Epub 2012 Sep 19. J Biol Chem. 2012. PMID: 22992727 Free PMC article.

2

Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents.

Sandur SK, Ichikawa H, Sethi G, Ahn KS, Aggarwal BB. Sandur SK, et al. Among authors: sethi g. J Biol Chem. 2006 Jun 23;281(25):17023-17033. doi: 10.1074/jbc.M601595200. Epub 2006 Apr 19. J Biol Chem. 2006. PMID: 16624823 Free article.

3

Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis.

Ahn KS, Sethi G, Jain AK, Jaiswal AK, Aggarwal BB. Ahn KS, et al. Among authors: sethi g. J Biol Chem. 2006 Jul 21;281(29):19798-808. doi: 10.1074/jbc.M601162200. Epub 2006 May 8. J Biol Chem. 2006. PMID: 16682409 Free article.

4

Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway.

Sethi G, Ahn KS, Sandur SK, Lin X, Chaturvedi MM, Aggarwal BB. Sethi G, et al. J Biol Chem. 2006 Aug 18;281(33):23425-35. doi: 10.1074/jbc.M602627200. Epub 2006 Jun 19. J Biol Chem. 2006. PMID: 16785236 Free article.

5

Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway.

Ahn KS, Sethi G, Shishodia S, Sung B, Arbiser JL, Aggarwal BB. Ahn KS, et al. Among authors: sethi g. Mol Cancer Res. 2006 Sep;4(9):621-33. doi: 10.1158/1541-7786.MCR-06-0076. Mol Cancer Res. 2006. PMID: 16966432

6

Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion.

Nair AS, Shishodia S, Ahn KS, Kunnumakkara AB, Sethi G, Aggarwal BB. Nair AS, et al. Among authors: sethi g. J Immunol. 2006 Oct 15;177(8):5612-22. doi: 10.4049/jimmunol.177.8.5612. J Immunol. 2006. PMID: 17015749

7

Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-kappaB (NF-kappaB) signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products.

Ahn KS, Sethi G, Aggarwal BB. Ahn KS, et al. Among authors: sethi g. Mol Pharmacol. 2007 Jan;71(1):209-19. doi: 10.1124/mol.106.028787. Epub 2006 Oct 6. Mol Pharmacol. 2007. PMID: 17028156

8

Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation.

Sethi G, Ahn KS, Pandey MK, Aggarwal BB. Sethi G, et al. Blood. 2007 Apr 1;109(7):2727-35. doi: 10.1182/blood-2006-10-050807. Blood. 2007. PMID: 17110449 Free article.

9

Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.

Ahn KS, Sethi G, Krishnan K, Aggarwal BB. Ahn KS, et al. Among authors: sethi g. J Biol Chem. 2007 Jan 5;282(1):809-20. doi: 10.1074/jbc.M610028200. Epub 2006 Nov 17. J Biol Chem. 2007. PMID: 17114179 Free article.

10

Simvastatin potentiates TNF-alpha-induced apoptosis through the down-regulation of NF-kappaB-dependent antiapoptotic gene products: role of IkappaBalpha kinase and TGF-beta-activated kinase-1.

Ahn KS, Sethi G, Aggarwal BB. Ahn KS, et al. Among authors: sethi g. J Immunol. 2007 Feb 15;178(4):2507-16. doi: 10.4049/jimmunol.178.4.2507. J Immunol. 2007. PMID: 17277159

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