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Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy.
Allen JA, Yost JM, Setola V, Chen X, Sassano MF, Chen M, Peterson S, Yadav PN, Huang XP, Feng B, Jensen NH, Che X, Bai X, Frye SV, Wetsel WC, Caron MG, Javitch JA, Roth BL, Jin J. Allen JA, et al. Among authors: setola v. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18488-93. doi: 10.1073/pnas.1104807108. Epub 2011 Oct 24. Proc Natl Acad Sci U S A. 2011. PMID: 22025698 Free PMC article.
Orally active adenosine A(1) receptor agonists with antinociceptive effects in mice.
Korboukh I, Hull-Ryde EA, Rittiner JE, Randhawa AS, Coleman J, Fitzpatrick BJ, Setola V, Janzen WP, Frye SV, Zylka MJ, Jin J. Korboukh I, et al. Among authors: setola v. J Med Chem. 2012 Jul 26;55(14):6467-77. doi: 10.1021/jm3004834. Epub 2012 Jul 16. J Med Chem. 2012. PMID: 22738238 Free PMC article.
Identification of a new selective dopamine D4 receptor ligand.
Sampson D, Zhu XY, Eyunni SV, Etukala JR, Ofori E, Bricker B, Lamango NS, Setola V, Roth BL, Ablordeppey SY. Sampson D, et al. Among authors: setola v. Bioorg Med Chem. 2014 Jun 15;22(12):3105-14. doi: 10.1016/j.bmc.2014.04.026. Epub 2014 Apr 20. Bioorg Med Chem. 2014. PMID: 24800940 Free PMC article.
Interaction of chiral MS-245 analogs at h5-HT6 receptors.
Abate C, Kolanos R, Dukat M, Setola V, Roth BL, Glennon RA. Abate C, et al. Among authors: setola v. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3510-3. doi: 10.1016/j.bmcl.2005.05.092. Bioorg Med Chem Lett. 2005. PMID: 15990303
1,2,3,4-tetrahydrocarbazoles as 5-HT6 serotonin receptor ligands.
Chang-Fong J, Rangisetty JB, Dukat M, Setola V, Raffay T, Roth B, Glennon RA. Chang-Fong J, et al. Among authors: setola v. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1961-4. doi: 10.1016/j.bmcl.2004.01.071. Bioorg Med Chem Lett. 2004. PMID: 15050637
85 results