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236 results
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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib.
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, Harris PL, Haserlat SM, Supko JG, Haluska FG, Louis DN, Christiani DC, Settleman J, Haber DA. Lynch TJ, et al. Among authors: settleman j. N Engl J Med. 2004 May 20;350(21):2129-39. doi: 10.1056/NEJMoa040938. Epub 2004 Apr 29. N Engl J Med. 2004. PMID: 15118073
Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
Perera RM, Stoykova S, Nicolay BN, Ross KN, Fitamant J, Boukhali M, Lengrand J, Deshpande V, Selig MK, Ferrone CR, Settleman J, Stephanopoulos G, Dyson NJ, Zoncu R, Ramaswamy S, Haas W, Bardeesy N. Perera RM, et al. Among authors: settleman j. Nature. 2015 Aug 20;524(7565):361-5. doi: 10.1038/nature14587. Epub 2015 Jul 13. Nature. 2015. PMID: 26168401 Free PMC article.
Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer.
Montagut C, Dalmases A, Bellosillo B, Crespo M, Pairet S, Iglesias M, Salido M, Gallen M, Marsters S, Tsai SP, Minoche A, Seshagiri S, Serrano S, Himmelbauer H, Bellmunt J, Rovira A, Settleman J, Bosch F, Albanell J. Montagut C, et al. Among authors: settleman j. Nat Med. 2012 Jan 22;18(2):221-3. doi: 10.1038/nm.2609. Nat Med. 2012. PMID: 22270724
TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers.
Singh A, Sweeney MF, Yu M, Burger A, Greninger P, Benes C, Haber DA, Settleman J. Singh A, et al. Among authors: settleman j. Cell. 2012 Feb 17;148(4):639-50. doi: 10.1016/j.cell.2011.12.033. Cell. 2012. PMID: 22341439 Free PMC article.
DOCK4, a GTPase activator, is disrupted during tumorigenesis.
Yajnik V, Paulding C, Sordella R, McClatchey AI, Saito M, Wahrer DC, Reynolds P, Bell DW, Lake R, van den Heuvel S, Settleman J, Haber DA. Yajnik V, et al. Among authors: settleman j. Cell. 2003 Mar 7;112(5):673-84. doi: 10.1016/s0092-8674(03)00155-7. Cell. 2003. PMID: 12628187
236 results