Settleman J - Search Results

1

Regulation of the nucleotide state of oncogenic ras proteins by nucleoside diphosphate kinase.

Fischbach MA, Settleman J. Fischbach MA, et al. Among authors: settleman j. Methods Enzymol. 2006;407:33-45. doi: 10.1016/S0076-6879(05)07004-7. Methods Enzymol. 2006. PMID: 16757312

2

Cell culture modeling of genotype-directed sensitivity to selective kinase inhibitors: targeting the anaplastic lymphoma kinase (ALK).

Settleman J. Settleman J. Semin Oncol. 2009 Apr;36(2 Suppl 1):S36-41. doi: 10.1053/j.seminoncol.2009.02.006. Semin Oncol. 2009. PMID: 19393834

3

TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers.

Singh A, Sweeney MF, Yu M, Burger A, Greninger P, Benes C, Haber DA, Settleman J. Singh A, et al. Among authors: settleman j. Cell. 2012 Feb 17;148(4):639-50. doi: 10.1016/j.cell.2011.12.033. Cell. 2012. PMID: 22341439 Free PMC article.

4

DOCK4, a GTPase activator, is disrupted during tumorigenesis.

Yajnik V, Paulding C, Sordella R, McClatchey AI, Saito M, Wahrer DC, Reynolds P, Bell DW, Lake R, van den Heuvel S, Settleman J, Haber DA. Yajnik V, et al. Among authors: settleman j. Cell. 2003 Mar 7;112(5):673-84. doi: 10.1016/s0092-8674(03)00155-7. Cell. 2003. PMID: 12628187

5

Exploiting the balance between life and death: targeted cancer therapy and "oncogenic shock".

Sharma SV, Settleman J. Sharma SV, et al. Among authors: settleman j. Biochem Pharmacol. 2010 Sep 1;80(5):666-73. doi: 10.1016/j.bcp.2010.03.001. Epub 2010 Mar 6. Biochem Pharmacol. 2010. PMID: 20211150 Review.

6

Personalized cancer therapy with selective kinase inhibitors: an emerging paradigm in medical oncology.

McDermott U, Settleman J. McDermott U, et al. Among authors: settleman j. J Clin Oncol. 2009 Nov 20;27(33):5650-9. doi: 10.1200/JCO.2009.22.9054. Epub 2009 Oct 26. J Clin Oncol. 2009. PMID: 19858389 Review.

7

Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas.

Kwak EL, Jankowski J, Thayer SP, Lauwers GY, Brannigan BW, Harris PL, Okimoto RA, Haserlat SM, Driscoll DR, Ferry D, Muir B, Settleman J, Fuchs CS, Kulke MH, Ryan DP, Clark JW, Sgroi DC, Haber DA, Bell DW. Kwak EL, et al. Among authors: settleman j. Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4283-7. doi: 10.1158/1078-0432.CCR-06-0189. Clin Cancer Res. 2006. PMID: 16857803 Free PMC article.

8

Rac 'n Rho: the music that shapes a developing embryo.

Settleman J. Settleman J. Dev Cell. 2001 Sep;1(3):321-31. doi: 10.1016/s1534-5807(01)00053-3. Dev Cell. 2001. PMID: 11702944 Review.

9

Inhibition of RhoGAP activity is sufficient for the induction of Rho-mediated actin reorganization.

Vincent S, Settleman J. Vincent S, et al. Among authors: settleman j. Eur J Cell Biol. 1999 Aug;78(8):539-48. doi: 10.1016/S0171-9335(99)80019-3. Eur J Cell Biol. 1999. PMID: 10494860

10

Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes.

Nolan KM, Barrett K, Lu Y, Hu KQ, Vincent S, Settleman J. Nolan KM, et al. Among authors: settleman j. Genes Dev. 1998 Nov 1;12(21):3337-42. doi: 10.1101/gad.12.21.3337. Genes Dev. 1998. PMID: 9808621 Free PMC article.

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