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TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers.
Singh A, Sweeney MF, Yu M, Burger A, Greninger P, Benes C, Haber DA, Settleman J. Singh A, et al. Among authors: settleman j. Cell. 2012 Feb 17;148(4):639-50. doi: 10.1016/j.cell.2011.12.033. Cell. 2012. PMID: 22341439 Free PMC article.
DOCK4, a GTPase activator, is disrupted during tumorigenesis.
Yajnik V, Paulding C, Sordella R, McClatchey AI, Saito M, Wahrer DC, Reynolds P, Bell DW, Lake R, van den Heuvel S, Settleman J, Haber DA. Yajnik V, et al. Among authors: settleman j. Cell. 2003 Mar 7;112(5):673-84. doi: 10.1016/s0092-8674(03)00155-7. Cell. 2003. PMID: 12628187
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations.
Sharma SV, Lee DY, Li B, Quinlan MP, Takahashi F, Maheswaran S, McDermott U, Azizian N, Zou L, Fischbach MA, Wong KK, Brandstetter K, Wittner B, Ramaswamy S, Classon M, Settleman J. Sharma SV, et al. Among authors: settleman j. Cell. 2010 Apr 2;141(1):69-80. doi: 10.1016/j.cell.2010.02.027. Cell. 2010. PMID: 20371346 Free PMC article.
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