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Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models.
Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, Hilfiker-Kleiner D, Wei C, Chen C, Tardi N, Hakroush S, Selig MK, Vasilyev A, Merscher S, Reiser J, Sever S. Schiffer M, et al. Among authors: sever s. Nat Med. 2015 Jun;21(6):601-9. doi: 10.1038/nm.3843. Epub 2015 May 11. Nat Med. 2015. PMID: 25962121 Free PMC article.
Establishment of protein delivery systems targeting podocytes.
Chiang WC, Geel TM, Altintas MM, Sever S, Ruiters MH, Reiser J. Chiang WC, et al. Among authors: sever s. PLoS One. 2010 Jul 29;5(7):e11837. doi: 10.1371/journal.pone.0011837. PLoS One. 2010. PMID: 20686602 Free PMC article.
Direct dynamin-actin interactions regulate the actin cytoskeleton.
Gu C, Yaddanapudi S, Weins A, Osborn T, Reiser J, Pollak M, Hartwig J, Sever S. Gu C, et al. Among authors: sever s. EMBO J. 2010 Nov 3;29(21):3593-606. doi: 10.1038/emboj.2010.249. Epub 2010 Oct 8. EMBO J. 2010. PMID: 20935625 Free PMC article.
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival.
Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst AL, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, Reinheckel T, Gu C, Huber TB, Ju W, Bitzer M, Rastaldi MP, Ruiz P, Tryggvason K, Shaw AS, Faul C, Sever S, Reiser J. Yaddanapudi S, et al. Among authors: sever s. J Clin Invest. 2011 Oct;121(10):3965-80. doi: 10.1172/JCI58552. Epub 2011 Sep 12. J Clin Invest. 2011. PMID: 21911934 Free PMC article.
Podocyte biology and pathogenesis of kidney disease.
Reiser J, Sever S. Reiser J, et al. Among authors: sever s. Annu Rev Med. 2013;64:357-66. doi: 10.1146/annurev-med-050311-163340. Epub 2012 Nov 26. Annu Rev Med. 2013. PMID: 23190150 Free PMC article. Review.
Is there clinical value in measuring suPAR levels in FSGS?
Sever S, Trachtman H, Wei C, Reiser J. Sever S, et al. Clin J Am Soc Nephrol. 2013 Aug;8(8):1273-5. doi: 10.2215/CJN.06170613. Epub 2013 Jul 25. Clin J Am Soc Nephrol. 2013. PMID: 23886567 Free PMC article. No abstract available.
Dynamin rings: not just for fission.
Sever S, Chang J, Gu C. Sever S, et al. Traffic. 2013 Dec;14(12):1194-9. doi: 10.1111/tra.12116. Epub 2013 Sep 19. Traffic. 2013. PMID: 23980695 Free PMC article. Review.
Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease.
Kistler AD, Singh G, Altintas MM, Yu H, Fernandez IC, Gu C, Wilson C, Srivastava SK, Dietrich A, Walz K, Kerjaschki D, Ruiz P, Dryer S, Sever S, Dinda AK, Faul C, Reiser J. Kistler AD, et al. Among authors: sever s. J Biol Chem. 2013 Dec 20;288(51):36598-609. doi: 10.1074/jbc.M113.488122. Epub 2013 Nov 5. J Biol Chem. 2013. PMID: 24194522 Free PMC article.
71 results