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Year Number of Results
1984 2
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1992 4
1993 2
1994 1
1995 1
1996 1
1997 3
1998 2
1999 2
2000 2
2001 3
2002 5
2003 6
2004 4
2005 8
2006 7
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2008 11
2009 8
2010 8
2011 11
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2013 28
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357 results

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Sex and gender differences in developmental programming of metabolism.
Dearden L, Bouret SG, Ozanne SE. Dearden L, et al. Mol Metab. 2018 Sep;15:8-19. doi: 10.1016/j.molmet.2018.04.007. Epub 2018 Apr 30. Mol Metab. 2018. PMID: 29773464 Free PMC article. Review.
BACKGROUND: The early life environment experienced by an individual in utero and during the neonatal period is a major factor in shaping later life disease risk-including susceptibility to develop obesity, diabetes, and cardiovascular disease. The incidence of metabolic di …
BACKGROUND: The early life environment experienced by an individual in utero and during the neonatal period is a major factor in shaping lat …
Understanding the broad influence of sex hormones and sex differences in the brain.
McEwen BS, Milner TA. McEwen BS, et al. J Neurosci Res. 2017 Jan 2;95(1-2):24-39. doi: 10.1002/jnr.23809. J Neurosci Res. 2017. PMID: 27870427 Free PMC article. Review.
Many neural and behavioral functions are affected, including mood, cognitive function, blood pressure regulation, motor coordination, pain, and opioid sensitivity. Subtle sex differences exist for many of these functions that are developmentally programmed
Many neural and behavioral functions are affected, including mood, cognitive function, blood pressure regulation, motor coordination, pain, …
DNA methylation networks underlying mammalian traits.
Haghani A, Li CZ, Robeck TR, Zhang J, Lu AT, Ablaeva J, Acosta-Rodríguez VA, Adams DM, Alagaili AN, Almunia J, Aloysius A, Amor NMS, Ardehali R, Arneson A, Baker CS, Banks G, Belov K, Bennett NC, Black P, Blumstein DT, Bors EK, Breeze CE, Brooke RT, Brown JL, Carter G, Caulton A, Cavin JM, Chakrabarti L, Chatzistamou I, Chavez AS, Chen H, Cheng K, Chiavellini P, Choi OW, Clarke S, Cook JA, Cooper LN, Cossette ML, Day J, DeYoung J, Dirocco S, Dold C, Dunnum JL, Ehmke EE, Emmons CK, Emmrich S, Erbay E, Erlacher-Reid C, Faulkes CG, Fei Z, Ferguson SH, Finno CJ, Flower JE, Gaillard JM, Garde E, Gerber L, Gladyshev VN, Goya RG, Grant MJ, Green CB, Hanson MB, Hart DW, Haulena M, Herrick K, Hogan AN, Hogg CJ, Hore TA, Huang T, Izpisua Belmonte JC, Jasinska AJ, Jones G, Jourdain E, Kashpur O, Katcher H, Katsumata E, Kaza V, Kiaris H, Kobor MS, Kordowitzki P, Koski WR, Krützen M, Kwon SB, Larison B, Lee SG, Lehmann M, Lemaître JF, Levine AJ, Li X, Li C, Lim AR, Lin DTS, Lindemann DM, Liphardt SW, Little TJ, Macoretta N, Maddox D, Matkin CO, Mattison JA, McClure M, Mergl J, Meudt JJ, Montano GA, Mozhui K, Munshi-South J, Murphy WJ, Naderi A, Nagy M, Narayan P, Nathanielsz PW, Nguyen NB, Nie… See abstract for full author list ➔ Haghani A, et al. Science. 2023 Aug 11;381(6658):eabq5693. doi: 10.1126/science.abq5693. Epub 2023 Aug 11. Science. 2023. PMID: 37561875
Using unsupervised clustering across all samples, we identified 55 distinct cytosine modules, of which 30 are related to traits such as maximum life span, adult weight, age, sex, and human mortality risk. Maximum life span is associated with methylation levels in HOXL subc …
Using unsupervised clustering across all samples, we identified 55 distinct cytosine modules, of which 30 are related to traits such as maxi …
Association of biological sex with clinical outcomes and biomarkers of Alzheimer's disease in adults with Down syndrome.
Iulita MF, Bejanin A, Vilaplana E, Carmona-Iragui M, Benejam B, Videla L, Barroeta I, Fernández S, Altuna M, Pegueroles J, Montal V, Valldeneu S, Giménez S, González-Ortiz S, Torres S, El Bounasri El Bennadi S, Padilla C, Rozalem Aranha M, Estellés T, Illán-Gala I, Belbin O, Valle-Tamayo N, Camacho V, Blessing E, Osorio RS, Videla S, Lehmann S, Holland AJ, Zetterberg H, Blennow K, Alcolea D, Clarimón J, Zaman SH, Blesa R, Lleó A, Fortea J. Iulita MF, et al. Brain Commun. 2023 Mar 17;5(2):fcad074. doi: 10.1093/braincomms/fcad074. eCollection 2023. Brain Commun. 2023. PMID: 37056479 Free PMC article.
The study of sex differences in Alzheimer's disease is increasingly recognized as a key priority in research and clinical development. ...Consideration of apolipoprotein e4 haplotype, particularly in females, may be important for clinical research and clinical trial …
The study of sex differences in Alzheimer's disease is increasingly recognized as a key priority in research and clinical deve …
Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly.
Li H, Janssens J, De Waegeneer M, Kolluru SS, Davie K, Gardeux V, Saelens W, David FPA, Brbić M, Spanier K, Leskovec J, McLaughlin CN, Xie Q, Jones RC, Brueckner K, Shim J, Tattikota SG, Schnorrer F, Rust K, Nystul TG, Carvalho-Santos Z, Ribeiro C, Pal S, Mahadevaraju S, Przytycka TM, Allen AM, Goodwin SF, Berry CW, Fuller MT, White-Cooper H, Matunis EL, DiNardo S, Galenza A, O'Brien LE, Dow JAT; FCA Consortium§; Jasper H, Oliver B, Perrimon N, Deplancke B, Quake SR, Luo L, Aerts S, Agarwal D, Ahmed-Braimah Y, Arbeitman M, Ariss MM, Augsburger J, Ayush K, Baker CC, Banisch T, Birker K, Bodmer R, Bolival B, Brantley SE, Brill JA, Brown NC, Buehner NA, Cai XT, Cardoso-Figueiredo R, Casares F, Chang A, Clandinin TR, Crasta S, Desplan C, Detweiler AM, Dhakan DB, Donà E, Engert S, Floc'hlay S, George N, González-Segarra AJ, Groves AK, Gumbin S, Guo Y, Harris DE, Heifetz Y, Holtz SL, Horns F, Hudry B, Hung RJ, Jan YN, Jaszczak JS, Jefferis GSXE, Karkanias J, Karr TL, Katheder NS, Kezos J, Kim AA, Kim SK, Kockel L, Konstantinides N, Kornberg TB, Krause HM, Labott AT, Laturney M, Lehmann R, Leinwand S, Li J, Li JSS, Li K, Li K, Li L, Li T, Litovchenko M, Liu HH, Liu Y, Lu TC, Manning J, M… See abstract for full author list ➔ Li H, et al. Science. 2022 Mar 4;375(6584):eabk2432. doi: 10.1126/science.abk2432. Epub 2022 Mar 4. Science. 2022. PMID: 35239393 Free PMC article.
Sex differences in the intergenerational inheritance of metabolic traits.
Sandovici I, Fernandez-Twinn DS, Hufnagel A, Constância M, Ozanne SE. Sandovici I, et al. Nat Metab. 2022 May;4(5):507-523. doi: 10.1038/s42255-022-00570-4. Epub 2022 May 30. Nat Metab. 2022. PMID: 35637347 Review.
Strong evidence suggests that early-life exposures to suboptimal environmental factors, including those in utero, influence our long-term metabolic health. This has been termed developmental programming. Mounting evidence suggests that the growth and metab
Strong evidence suggests that early-life exposures to suboptimal environmental factors, including those in utero, influence our long-term …
Mechanisms involved in developmental programming of hypertension and renal diseases. Gender differences.
Tomat AL, Salazar FJ. Tomat AL, et al. Horm Mol Biol Clin Investig. 2014 May;18(2):63-77. doi: 10.1515/hmbci-2013-0054. Horm Mol Biol Clin Investig. 2014. PMID: 25390003 Review.
Moreover, this review highlights important sex-dependent differences in the adaptation to developmental insults. ...Future studies are needed in order to prevent the origin and reduce the incidence and consequences of developmental programmed di …
Moreover, this review highlights important sex-dependent differences in the adaptation to developmental insults. ...Fut …
Sex-specific differences and developmental programming for diseases in later life.
Sundrani DP, Roy SS, Jadhav AT, Joshi SR. Sundrani DP, et al. Reprod Fertil Dev. 2017 Oct;29(11):2085-2099. doi: 10.1071/RD16265. Reprod Fertil Dev. 2017. PMID: 28380326 Review.
Sex-specific differences have also been reported in most NCDs. Evidence suggests that beginning from conception, the maternal and neonatal metabolic environment, including hormones, contributes to sex-specific placental development. ...This review summ
Sex-specific differences have also been reported in most NCDs. Evidence suggests that beginning from conception, the maternal
Maternal immune activation in mice disrupts proteostasis in the fetal brain.
Kalish BT, Kim E, Finander B, Duffy EE, Kim H, Gilman CK, Yim YS, Tong L, Kaufman RJ, Griffith EC, Choi GB, Greenberg ME, Huh JR. Kalish BT, et al. Nat Neurosci. 2021 Feb;24(2):204-213. doi: 10.1038/s41593-020-00762-9. Epub 2020 Dec 23. Nat Neurosci. 2021. PMID: 33361822 Free PMC article.
Moreover, blockade of ISR activation prevented the behavioral abnormalities as well as increased cortical neural activity in MIA male offspring. Our data suggest that sex-specific activation of the ISR leads to maternal inflammation-associated neurodevelopmental disorders. …
Moreover, blockade of ISR activation prevented the behavioral abnormalities as well as increased cortical neural activity in MIA male offspr …
Surprising origins of sex differences in the brain.
McCarthy MM, Pickett LA, VanRyzin JW, Kight KE. McCarthy MM, et al. Horm Behav. 2015 Nov;76:3-10. doi: 10.1016/j.yhbeh.2015.04.013. Epub 2015 Apr 25. Horm Behav. 2015. PMID: 25917865 Free PMC article. Review.
Sex differences in the brain include regional volume differences due to differential cell death, neuronal and glial genesis, dendritic branching and synaptic patterning. ...We propose that some neuroanatomical endpoints are canalized to enhance sex
Sex differences in the brain include regional volume differences due to differential cell death, neuronal and glial gen
357 results