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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 2
1998 1
1999 1
2000 1
2002 1
2009 1
2010 3
2011 2
2012 1
2015 1
2016 2
2017 5
2018 4
2019 9
2020 2
2021 0
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Sex differences in the genetic predictors of Alzheimer's pathology.
Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Bush WS, Gifford KA, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Deming Y, Chao MJ, Huentelman M, Martin ER, Hamilton-Nelson K, Shaw LM, Trojanowski JQ, Peskind ER, Cruchaga C, Pericak-Vance MA, Goate AM, Cox NJ, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M; Alzheimer’s Disease Genetics Consortium and the Alzheimer’s Disease Neuroimaging Initiative, Bennett DA, Schneider JA, Jefferson AL, Hohman TJ. Dumitrescu L, et al. Brain. 2019 Sep 1;142(9):2581-2589. doi: 10.1093/brain/awz206. Brain. 2019. PMID: 31497858 Free PMC article.
However, despite evidence of sex differences in Alzheimer's disease risk, sex-stratified models have not been incorporated into previous GWAS analyses. We looked for sex-specific genetic associations with Alzheimer' …
However, despite evidence of sex differences in Alzheimer's disease risk, sex-stratified models ha …
Sex Differences in the Genetic Architecture of Alzheimer's Disease.
Dumitrescu L, Mayeda ER, Sharman K, Moore AM, Hohman TJ. Dumitrescu L, et al. Curr Genet Med Rep. 2019 Mar;7(1):13-21. doi: 10.1007/s40142-019-0157-1. Epub 2019 Jan 21. Curr Genet Med Rep. 2019. PMID: 31360619 Free PMC article.
PURPOSE OF REVIEW: Summarize sex-specific contributors to the genetic architecture of Alzheimer's disease (AD). ...SUMMARY: There is a lack of comprehensive assessments of sex differences in genome-wide analyses of AD and a need fo …
PURPOSE OF REVIEW: Summarize sex-specific contributors to the genetic architecture of Alzheimer's disease
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Moghekar A, Del Aguila JL, Fernandez MV, Budde J, Hassenstab J, Fagan AM, Riemenschneider M, Petersen RC, Minthon L, Chao MJ, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Peskind ER, Li G, Davis LK, Sealock JM, Cox NJ; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer Disease Genetics Consortium (ADGC), Goate AM, Bennett DA, Schneider JA, Jefferson AL, Cruchaga C, Hohman TJ. Deming Y, et al. Acta Neuropathol. 2018 Dec;136(6):857-872. doi: 10.1007/s00401-018-1881-4. Epub 2018 Jul 2. Acta Neuropathol. 2018. PMID: 29967939 Free PMC article.
Cerebrospinal fluid (CSF) levels of amyloid-beta 42 (Abeta42) and tau have been evaluated as endophenotypes in Alzheimer's disease (AD) genetic studies. Although there are sex differences in AD risk, sex differences have not …
Cerebrospinal fluid (CSF) levels of amyloid-beta 42 (Abeta42) and tau have been evaluated as endophenotypes in Alzheimer's
Models for predicting risk of dementia: a systematic review.
Hou XH, Feng L, Zhang C, Cao XP, Tan L, Yu JT. Hou XH, et al. J Neurol Neurosurg Psychiatry. 2019 Apr;90(4):373-379. doi: 10.1136/jnnp-2018-318212. Epub 2018 Jun 28. J Neurol Neurosurg Psychiatry. 2019. PMID: 29954871
RESULTS: Of 8462 studies reviewed, 61 articles describing dementia risk models were identified, with the majority of the articles modelling late life risk (n=39), followed by those modelling prediction of mild cognitive impairment to Alzheimer's disease (n=15 …
RESULTS: Of 8462 studies reviewed, 61 articles describing dementia risk models were identified, with the majority of the articles modelling …
Sex-driven modifiers of Alzheimer risk: A multimodality brain imaging study.
Rahman A, Schelbaum E, Hoffman K, Diaz I, Hristov H, Andrews R, Jett S, Jackson H, Lee A, Sarva H, Pahlajani S, Matthews D, Dyke J, de Leon MJ, Isaacson RS, Brinton RD, Mosconi L. Rahman A, et al. Neurology. 2020 Jul 14;95(2):e166-e178. doi: 10.1212/WNL.0000000000009781. Epub 2020 Jun 24. Neurology. 2020. PMID: 32580974
OBJECTIVE: To investigate sex differences in late-onset Alzheimer disease (AD) risks by means of multimodality brain biomarkers (beta-amyloid load via (11)C-Pittsburgh compound B [PiB] PET, neurodegeneration via (18)F-fluorodeoxyglucose [FDG] PET and s …
OBJECTIVE: To investigate sex differences in late-onset Alzheimer disease (AD) risks by means of multimodality b …
Predictors of Heterogeneity in Cognitive Function: APOE-e4, Sex, Education, Depression, and Vascular Risk.
MacAulay RK, Halpin A, Cohen AS, Calamia M, Boeve A, Zhang L, Brouillette RM, Foil HC, Bruce-Keller A, Keller JN. MacAulay RK, et al. Arch Clin Neuropsychol. 2020 Aug 28;35(6):660-670. doi: 10.1093/arclin/acaa014. Arch Clin Neuropsychol. 2020. PMID: 32129455
RESULTS: The hypothesized model(s) provided an adequate fit for the data. Sex differences in cognition, depression, and vascular risk were found. ...Future research is needed to determine whether the multifactorial risk effects on cognition vary by sex
RESULTS: The hypothesized model(s) provided an adequate fit for the data. Sex differences in cognition, depression, and …
Identification of Successful Cognitive Aging in the Alzheimer's Disease Neuroimaging Initiative Study.
Lin FV, Wang X, Wu R, Rebok GW, Chapman BP; Alzheimer’s Disease Neuroimaging Initiative. Lin FV, et al. J Alzheimers Dis. 2017;59(1):101-111. doi: 10.3233/JAD-161278. J Alzheimers Dis. 2017. PMID: 28582857 Free PMC article.
Potential individual-level predictors that were related to Alzheimer's disease pathology or genetic risk, neurodegeneration, and vascular risks were collected at baseline. ...Sex, apolipoprotein E allele 4, amyloid-beta1-42, and t-tau sig …
Potential individual-level predictors that were related to Alzheimer's disease pathology or genetic risk, …
Early- versus late-onset Alzheimer's disease in clinical practice: cognitive and global outcomes over 3 years.
Wattmo C, Wallin ÅK. Wattmo C, et al. Alzheimers Res Ther. 2017 Aug 31;9(1):70. doi: 10.1186/s13195-017-0294-2. Alzheimers Res Ther. 2017. PMID: 28859660 Free PMC article.
BACKGROUND: Whether age at onset influences Alzheimer's disease (AD) progression and the effectiveness of cholinesterase inhibitor (ChEI) therapy is not clear. We aimed to compare longitudinal cognitive and global outcomes in ChEI-treated patients with …
BACKGROUND: Whether age at onset influences Alzheimer's disease (AD) progression and the effectiveness of cholinesteras …
Physical activity, diet, and risk of Alzheimer disease.
Scarmeas N, Luchsinger JA, Schupf N, Brickman AM, Cosentino S, Tang MX, Stern Y. Scarmeas N, et al. JAMA. 2009 Aug 12;302(6):627-37. doi: 10.1001/jama.2009.1144. JAMA. 2009. PMID: 19671904 Free PMC article.
CONTEXT: Both higher adherence to a Mediterranean-type diet and more physical activity have been independently associated with lower Alzheimer disease (AD) risk but their combined association has not been investigated. ...Adherence to a Mediterranean-type diet (scal …
CONTEXT: Both higher adherence to a Mediterranean-type diet and more physical activity have been independently associated with lower Alzh
Promoter polymorphism (-491A/T) in the APOE gene of Finnish Alzheimer's disease patients and control individuals.
Helisalmi S, Hiltunen M, Valonen P, Mannermaa A, Koivisto AM, Lehtovirta M, Ryynänen M, Soininen H. Helisalmi S, et al. J Neurol. 1999 Sep;246(9):821-4. doi: 10.1007/s004150050461. J Neurol. 1999. PMID: 10525981 Clinical Trial.
Apolipoprotein E (APOE) epsilon4 allele is a major risk factor for the development of Alzheimer's disease (AD). It has been suggested that the quantitative expression of APOE alleles results from mutations in the promoter region of this gene. ...Our findings …
Apolipoprotein E (APOE) epsilon4 allele is a major risk factor for the development of Alzheimer's disease (AD). It has …
33 results
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