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Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection.
Channappanavar R, Fett C, Mack M, Ten Eyck PP, Meyerholz DK, Perlman S. Channappanavar R, et al. J Immunol. 2017 May 15;198(10):4046-4053. doi: 10.4049/jimmunol.1601896. Epub 2017 Apr 3. J Immunol. 2017. PMID: 28373583 Free PMC article.
Pathogenic human coronaviruses (CoVs), such as the severe acute respiratory syndrome (SARS)-CoV and the Middle East respiratory syndrome-CoV, cause acute respiratory illness. ...To investigate these d
Pathogenic human coronaviruses (CoVs), such as the severe acute respiratory syndrome (SARS)-CoV an …
Sex differences in immune responses to SARS-CoV-2 that underlie disease outcomes.
Takahashi T, Wong P, Ellingson MK, Lucas C, Klein J, Israelow B, Silva J, Oh JE, Mao T, Tokuyama M, Lu P, Venkataraman A, Park A, Liu F, Meir A, Sun J, Wang EY, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ, Casanovas-Massana A, Cruz CD, Fournier JB, Odio CD, Farhadian S, Grubaugh ND, Schulz WL, Ko AI, Ring AM, Omer SB, Iwasaki A; Yale IMPACT research team. Takahashi T, et al. medRxiv. 2020 Jun 9:2020.06.06.20123414. doi: 10.1101/2020.06.06.20123414. Preprint. medRxiv. 2020. PMID: 32577695 Free PMC article. Updated.
However, whether immune responses against SARS-CoV-2 differ between sexes, and whether such differences explain male susceptibility to COVID-19, is currently unknown. In this study, we examined sex differences in viral loads, SA
However, whether immune responses against SARS-CoV-2 differ between sexes, and whether such differences explain …
What's Sex Got to Do With COVID-19? Gender-Based Differences in the Host Immune Response to Coronaviruses.
Gadi N, Wu SC, Spihlman AP, Moulton VR. Gadi N, et al. Front Immunol. 2020 Aug 28;11:2147. doi: 10.3389/fimmu.2020.02147. eCollection 2020. Front Immunol. 2020. PMID: 32983176 Free PMC article. Review.
The novel severe acute respiratory syndrome coronavirus 2, the cause of the coronavirus disease 2019 (COVID-19) pandemic, has ravaged the world, with over 22 million total cases and over 770,000 deaths worldwide as of August 18, 2020. ...Women m …
The novel severe acute respiratory syndrome coronavirus 2, the cause of the coronavirus disease 2019 (COV …
Is COVID-19 Gender-sensitive?
Mukherjee S, Pahan K. Mukherjee S, et al. J Neuroimmune Pharmacol. 2021 Mar;16(1):38-47. doi: 10.1007/s11481-020-09974-z. Epub 2021 Jan 6. J Neuroimmune Pharmacol. 2021. PMID: 33405098 Free PMC article. Review.
Thus, sex-based differences in the expression of the ACE2 receptor and TMPRSS2 may explain the disparities in COVID-19 severity and fatality. Furthermore, these disparities may also be attributed to sex-based difference in immunological r …
Thus, sex-based differences in the expression of the ACE2 receptor and TMPRSS2 may explain the disparities in COVID-19 …
SeXX and COVID-19: tussle between the two.
Patil A, Tripathy JP, Deshmukh V, Sontakke B, Tripathi SC. Patil A, et al. Monaldi Arch Chest Dis. 2020 Sep 18;90(4). doi: 10.4081/monaldi.2020.1461. Monaldi Arch Chest Dis. 2020. PMID: 32945643 Free article. Review.
There are several reports of gender differences related to infection and death due to COVID-19. This raises important questions such as "Whether there are differences based on gender in risk and severity of infection or mortality rate?" ...This …
There are several reports of gender differences related to infection and death due to COVID-19. This raises important question …
A comprehensive investigation of the mRNA and protein level of ACE2, the putative receptor of SARS-CoV-2, in human tissues and blood cells.
Wang Y, Wang Y, Luo W, Huang L, Xiao J, Li F, Qin S, Song X, Wu Y, Zeng Q, Jin F, Wang Y. Wang Y, et al. Int J Med Sci. 2020 Jun 18;17(11):1522-1531. doi: 10.7150/ijms.46695. eCollection 2020. Int J Med Sci. 2020. PMID: 32669955 Free PMC article.
Angiotensin-converting enzyme 2 (ACE2) was identified as a functional receptor for SARS-CoV-2, distribution of which may indicate the risk of different human organs vulnerable to SARS-CoV-2 infection. ...Our research will be beneficial fo …
Angiotensin-converting enzyme 2 (ACE2) was identified as a functional receptor for SARS-CoV-2, distribution of which may indic …
Type I IFN-dependent antibody response at the basis of sex dimorphism in the outcome of COVID-19.
Gabriele L, Fragale A, Romagnoli G, Parlato S, Lapenta C, Santini SM, Ozato K, Capone I. Gabriele L, et al. Cytokine Growth Factor Rev. 2021 Apr;58:66-74. doi: 10.1016/j.cytogfr.2020.10.001. Epub 2020 Oct 8. Cytokine Growth Factor Rev. 2021. PMID: 33071044 Free PMC article. Review.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic, induces severe pneumonia mainly in elderly males. Epidemiological data clearly in
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the ongoing c
The Physiological Mechanisms of the Sex-Based Difference in Outcomes of COVID19 Infection.
Wray S, Arrowsmith S. Wray S, et al. Front Physiol. 2021 Feb 9;12:627260. doi: 10.3389/fphys.2021.627260. eCollection 2021. Front Physiol. 2021. PMID: 33633588 Free PMC article. Review.
The scale of the SARS-CoV-2 pandemic has thrust a spotlight on the sex-based differences in response to viral diseases; morbidity and mortality are greater in men than women. ...The physiological and immunological mechanisms are fascinating and …
The scale of the SARS-CoV-2 pandemic has thrust a spotlight on the sex-based differences in response to v …
An overview of Betacoronaviruses-associated severe respiratory syndromes, focusing on sex-type-specific immune responses.
Rahimi G, Rahimi B, Panahi M, Abkhiz S, Saraygord-Afshari N, Milani M, Alizadeh E. Rahimi G, et al. Int Immunopharmacol. 2021 Mar;92:107365. doi: 10.1016/j.intimp.2021.107365. Epub 2021 Jan 10. Int Immunopharmacol. 2021. PMID: 33440306 Free PMC article. Review.
Emerging beta-coronaviruses (beta-CoVs), including Severe Acute Respiratory Syndrome CoV-1 (SARS-CoV-1), Middle East Respiratory Syndrome-CoV (MERS-CoV), and Severe Acute Respiratory
Emerging beta-coronaviruses (beta-CoVs), including Severe Acute Respiratory Syndrome CoV-1 (SARS- …
Prevalence of COVID-19 Virus Infection in Semnan province.
Jandaghi E, Hemati M, Mohammadlou M, Jandaghi J, Mirmohammadkhani M, Danaei N, Kokhaei P. Jandaghi E, et al. Iran J Immunol. 2021 Mar;18(1):74-81. doi: 10.22034/iji.2021.87670.1826. Iran J Immunol. 2021. PMID: 33787516 Free article.
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) causing a human pandemic disease named COVID-19 has become a major global health concern. ...Among total participants, the age and sex adjusted preval …
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) causing a human pandemic …
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