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333 results
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Light-activated chimeric GPCRs: limitations and opportunities.
Tichy AM, Gerrard EJ, Sexton PM, Janovjak H. Tichy AM, et al. Among authors: sexton pm. Curr Opin Struct Biol. 2019 Aug;57:196-203. doi: 10.1016/ Epub 2019 Jun 14. Curr Opin Struct Biol. 2019. PMID: 31207383 Review.
Homology modeling of GPCRs.
Simms J, Hall NE, Lam PH, Miller LJ, Christopoulos A, Abagyan R, Sexton PM. Simms J, et al. Among authors: sexton pm. Methods Mol Biol. 2009;552:97-113. doi: 10.1007/978-1-60327-317-6_7. Methods Mol Biol. 2009. PMID: 19513644
Allostery in GPCRs: 'MWC' revisited.
Canals M, Sexton PM, Christopoulos A. Canals M, et al. Among authors: sexton pm. Trends Biochem Sci. 2011 Dec;36(12):663-72. doi: 10.1016/j.tibs.2011.08.005. Epub 2011 Sep 14. Trends Biochem Sci. 2011. PMID: 21920759 Review.
Novel Allosteric Modulators of G Protein-coupled Receptors.
Gentry PR, Sexton PM, Christopoulos A. Gentry PR, et al. Among authors: sexton pm. J Biol Chem. 2015 Aug 7;290(32):19478-88. doi: 10.1074/jbc.R115.662759. Epub 2015 Jun 22. J Biol Chem. 2015. PMID: 26100627 Free PMC article. Review.
The role of kinetic context in apparent biased agonism at GPCRs.
Klein Herenbrink C, Sykes DA, Donthamsetti P, Canals M, Coudrat T, Shonberg J, Scammells PJ, Capuano B, Sexton PM, Charlton SJ, Javitch JA, Christopoulos A, Lane JR. Klein Herenbrink C, et al. Among authors: sexton pm. Nat Commun. 2016 Feb 24;7:10842. doi: 10.1038/ncomms10842. Nat Commun. 2016. PMID: 26905976 Free PMC article.
333 results