Seymour LW - Search Results

1

Passive tumor targeting of soluble macromolecules and drug conjugates.

Seymour LW. Seymour LW. Crit Rev Ther Drug Carrier Syst. 1992;9(2):135-87. Crit Rev Ther Drug Carrier Syst. 1992. PMID: 1386002 Review.

2

The pharmacokinetics of polymer-bound adriamycin.

Seymour LW, Ulbrich K, Strohalm J, Kopecek J, Duncan R. Seymour LW, et al. Biochem Pharmacol. 1990 Mar 15;39(6):1125-31. doi: 10.1016/0006-2952(90)90293-t. Biochem Pharmacol. 1990. PMID: 2322298

3

Effect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats.

Seymour LW, Duncan R, Strohalm J, Kopecek J. Seymour LW, et al. J Biomed Mater Res. 1987 Nov;21(11):1341-58. doi: 10.1002/jbm.820211106. J Biomed Mater Res. 1987. PMID: 3680316

4

Daunomycin- and adriamycin-N-(2-hydroxypropyl)methacrylamide copolymer conjugates; toxicity reduction by improved drug-delivery.

Seymour LW, Duncan R, Kopecková P, Kopecek J. Seymour LW, et al. Cancer Treat Rev. 1987 Dec;14(3-4):319-27. doi: 10.1016/0305-7372(87)90024-7. Cancer Treat Rev. 1987. PMID: 3326668 Review. No abstract available.

5

Synthetic polymers conjugated to monoclonal antibodies: vehicles for tumour-targeted drug delivery.

Seymour LW, Flanagan PA, al-Shamkhani A, Subr V, Ulbrich K, Cassidy J, Duncan R. Seymour LW, et al. Sel Cancer Ther. 1991 Summer;7(2):59-73. doi: 10.1089/sct.1991.7.59. Sel Cancer Ther. 1991. PMID: 1754729

6

N-(2-hydroxypropyl)methacrylamide copolymers targeted to the hepatocyte galactose-receptor: pharmacokinetics in DBA2 mice.

Seymour LW, Ulbrich K, Wedge SR, Hume IC, Strohalm J, Duncan R. Seymour LW, et al. Br J Cancer. 1991 Jun;63(6):859-66. doi: 10.1038/bjc.1991.190. Br J Cancer. 1991. PMID: 1648946 Free PMC article.

7

A novel dosage approach for evaluation of SMANCS [poly-(styrene-co-maleyl-half-n-butylate) - neocarzinostatin] in the treatment of primary hepatocellular carcinoma.

Seymour LW, Olliff SP, Poole CJ, De Takats PG, Orme R, Ferry DR, Maeda H, Konno T, Kerr DJ. Seymour LW, et al. Int J Oncol. 1998 Jun;12(6):1217-23. doi: 10.3892/ijo.12.6.1217. Int J Oncol. 1998. PMID: 9592177 Clinical Trial.

8

Reduced cardiotoxicity of doxorubicin given in the form of N-(2-hydroxypropyl)methacrylamide conjugates: and experimental study in the rat.

Yeung TK, Hopewell JW, Simmonds RH, Seymour LW, Duncan R, Bellini O, Grandi M, Spreafico F, Strohalm J, Ulbrich K. Yeung TK, et al. Among authors: seymour lw. Cancer Chemother Pharmacol. 1991;29(2):105-11. doi: 10.1007/BF00687318. Cancer Chemother Pharmacol. 1991. PMID: 1760851

9

Polymeric prodrugs of mitomycin C designed for tumour tropism and sustained activation.

Seymour LW, Soyez H, De Marre A, Shoaibi MA, Schacht EH. Seymour LW, et al. Anticancer Drug Des. 1996 Jul;11(5):351-65. Anticancer Drug Des. 1996. PMID: 8765529

10

Systemic circulation of poly(L-lysine)/DNA vectors is influenced by polycation molecular weight and type of DNA: differential circulation in mice and rats and the implications for human gene therapy.

Ward CM, Read ML, Seymour LW. Ward CM, et al. Among authors: seymour lw. Blood. 2001 Apr 15;97(8):2221-9. doi: 10.1182/blood.v97.8.2221. Blood. 2001. PMID: 11290582

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