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1964 1
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58 results

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Page 1
RHINO directs MMEJ to repair DNA breaks in mitosis.
Brambati A, Sacco O, Porcella S, Heyza J, Kareh M, Schmidt JC, Sfeir A. Brambati A, et al. Among authors: sfeir a. Science. 2023 Aug 11;381(6658):653-660. doi: 10.1126/science.adh3694. Epub 2023 Jul 13. Science. 2023. PMID: 37440612 Free PMC article.
Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ.
Bubenik M, Mader P, Mochirian P, Vallée F, Clark J, Truchon JF, Perryman AL, Pau V, Kurinov I, Zahn KE, Leclaire ME, Papp R, Mathieu MC, Hamel M, Duffy NM, Godbout C, Casas-Selves M, Falgueyret JP, Baruah PS, Nicolas O, Stocco R, Poirier H, Martino G, Fortin AB, Roulston A, Chefson A, Dorich S, St-Onge M, Patel P, Pellerin C, Ciblat S, Pinter T, Barabé F, El Bakkouri M, Parikh P, Gervais C, Sfeir A, Mamane Y, Morris SJ, Black WC, Sicheri F, Gallant M. Bubenik M, et al. Among authors: sfeir a. J Med Chem. 2022 Oct 13;65(19):13198-13215. doi: 10.1021/acs.jmedchem.2c00998. Epub 2022 Sep 20. J Med Chem. 2022. PMID: 36126059 Free PMC article.
POLQ inhibition elicits an immune response in homologous recombination-deficient pancreatic adenocarcinoma via cGAS/STING signaling.
Oh G, Wang A, Wang L, Li J, Werba G, Weissinger D, Zhao E, Dhara S, Hernandez RE, Ackermann A, Porcella S, Kalfakakou D, Dolgalev I, Kawaler E, Golan T, Welling TH, Sfeir A, Simeone DM. Oh G, et al. Among authors: sfeir a. J Clin Invest. 2023 Jun 1;133(11):e165934. doi: 10.1172/JCI165934. J Clin Invest. 2023. PMID: 36976649 Free PMC article.
Safeguarding mitochondrial genomes in higher eukaryotes.
Fu Y, Tigano M, Sfeir A. Fu Y, et al. Among authors: sfeir a. Nat Struct Mol Biol. 2020 Aug;27(8):687-695. doi: 10.1038/s41594-020-0474-9. Epub 2020 Aug 6. Nat Struct Mol Biol. 2020. PMID: 32764737 Review.
Telomeres at a glance.
Sfeir A. Sfeir A. J Cell Sci. 2012 Sep 15;125(Pt 18):4173-8. doi: 10.1242/jcs.106831. J Cell Sci. 2012. PMID: 23135002 Free PMC article. Review. No abstract available.
Basic science under threat: Lessons from the Skirball Institute.
Sfeir A, Fishell G, Schier AF, Dustin ML, Gan WB, Joyner A, Lehmann R, Ron D, Roth D, Talbot WS, Yelon D, Zychlinsky A. Sfeir A, et al. Cell. 2022 Mar 3;185(5):755-758. doi: 10.1016/j.cell.2022.02.008. Cell. 2022. PMID: 35245477 Free article.
Stressed telomeres without POT1 enhance tumorigenesis.
Sfeir A, Denchi EL. Sfeir A, et al. Oncotarget. 2016 Jul 26;7(30):46833-46834. doi: 10.18632/oncotarget.10600. Oncotarget. 2016. PMID: 27419638 Free PMC article. No abstract available.
58 results