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Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses.
Sha WC, Liou HC, Tuomanen EI, Baltimore D. Sha WC, et al. Cell. 1995 Jan 27;80(2):321-30. doi: 10.1016/0092-8674(95)90415-8. Cell. 1995. PMID: 7834752
The combined absence of NF-kappa B1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells.
Pohl T, Gugasyan R, Grumont RJ, Strasser A, Metcalf D, Tarlinton D, Sha W, Baltimore D, Gerondakis S. Pohl T, et al. Among authors: sha w. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4514-9. doi: 10.1073/pnas.072071599. Proc Natl Acad Sci U S A. 2002. PMID: 11930006 Free PMC article.
Regulation of Ig class switch recombination by NF-kappaB: retroviral expression of RelB in activated B cells inhibits switching to IgG1, but not to IgE.
Bhattacharya D, Lee DU, Sha WC. Bhattacharya D, et al. Among authors: sha wc. Int Immunol. 2002 Sep;14(9):983-91. doi: 10.1093/intimm/dxf066. Int Immunol. 2002. PMID: 12202396
Redundant role of tissue-selective TAF(II)105 in B lymphocytes.
Freiman RN, Albright SR, Chu LE, Zheng S, Liang HE, Sha WC, Tjian R. Freiman RN, et al. Among authors: sha wc. Mol Cell Biol. 2002 Sep;22(18):6564-72. doi: 10.1128/mcb.22.18.6564-6572.2002. Mol Cell Biol. 2002. PMID: 12192054 Free PMC article.
Regulation of immune responses by NF-kappa B/Rel transcription factor.
Sha WC. Sha WC. J Exp Med. 1998 Jan 19;187(2):143-6. doi: 10.1084/jem.187.2.143. J Exp Med. 1998. PMID: 9432972 Free PMC article. Review. No abstract available.
Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation.
Liou HC, Sha WC, Scott ML, Baltimore D. Liou HC, et al. Among authors: sha wc. Mol Cell Biol. 1994 Aug;14(8):5349-59. doi: 10.1128/mcb.14.8.5349. Mol Cell Biol. 1994. PMID: 8035813 Free PMC article.
Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice.
Beg AA, Sha WC, Bronson RT, Baltimore D. Beg AA, et al. Among authors: sha wc. Genes Dev. 1995 Nov 15;9(22):2736-46. doi: 10.1101/gad.9.22.2736. Genes Dev. 1995. PMID: 7590249
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B.
Beg AA, Sha WC, Bronson RT, Ghosh S, Baltimore D. Beg AA, et al. Among authors: sha wc. Nature. 1995 Jul 13;376(6536):167-70. doi: 10.1038/376167a0. Nature. 1995. PMID: 7603567
B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching.
Snapper CM, Zelazowski P, Rosas FR, Kehry MR, Tian M, Baltimore D, Sha WC. Snapper CM, et al. Among authors: sha wc. J Immunol. 1996 Jan 1;156(1):183-91. J Immunol. 1996. PMID: 8598461
Regulation of 3' IgH enhancers by a common set of factors, including kappa B-binding proteins.
Michaelson JS, Singh M, Snapper CM, Sha WC, Baltimore D, Birshtein BK. Michaelson JS, et al. Among authors: sha wc. J Immunol. 1996 Apr 15;156(8):2828-39. J Immunol. 1996. PMID: 8609402
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