Shaaltiel Y - Search Results

1

Large-scale production of pharmaceutical proteins in plant cell culture-the Protalix experience.

Tekoah Y, Shulman A, Kizhner T, Ruderfer I, Fux L, Nataf Y, Bartfeld D, Ariel T, Gingis-Velitski S, Hanania U, Shaaltiel Y. Tekoah Y, et al. Among authors: shaaltiel y. Plant Biotechnol J. 2015 Oct;13(8):1199-208. doi: 10.1111/pbi.12428. Epub 2015 Jun 23. Plant Biotechnol J. 2015. PMID: 26102075 Free article. Review.

2

Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system.

Shaaltiel Y, Bartfeld D, Hashmueli S, Baum G, Brill-Almon E, Galili G, Dym O, Boldin-Adamsky SA, Silman I, Sussman JL, Futerman AH, Aviezer D. Shaaltiel Y, et al. Plant Biotechnol J. 2007 Sep;5(5):579-90. doi: 10.1111/j.1467-7652.2007.00263.x. Epub 2007 May 24. Plant Biotechnol J. 2007. PMID: 17524049 Free article.

3

Plant-based oral delivery of β-glucocerebrosidase as an enzyme replacement therapy for Gaucher's disease.

Shaaltiel Y, Gingis-Velitski S, Tzaban S, Fiks N, Tekoah Y, Aviezer D. Shaaltiel Y, et al. Plant Biotechnol J. 2015 Oct;13(8):1033-40. doi: 10.1111/pbi.12366. Epub 2015 Apr 1. Plant Biotechnol J. 2015. PMID: 25828481 Free article.

4

Establishment of a tobacco BY2 cell line devoid of plant-specific xylose and fucose as a platform for the production of biotherapeutic proteins.

Hanania U, Ariel T, Tekoah Y, Fux L, Sheva M, Gubbay Y, Weiss M, Oz D, Azulay Y, Turbovski A, Forster Y, Shaaltiel Y. Hanania U, et al. Among authors: shaaltiel y. Plant Biotechnol J. 2017 Sep;15(9):1120-1129. doi: 10.1111/pbi.12702. Epub 2017 Mar 3. Plant Biotechnol J. 2017. PMID: 28160363 Free PMC article.

5

Glycosylation and functionality of recombinant β-glucocerebrosidase from various production systems.

Tekoah Y, Tzaban S, Kizhner T, Hainrichson M, Gantman A, Golembo M, Aviezer D, Shaaltiel Y. Tekoah Y, et al. Among authors: shaaltiel y. Biosci Rep. 2013 Sep 25;33(5):e00071. doi: 10.1042/BSR20130081. Biosci Rep. 2013. PMID: 23980545 Free PMC article.

6

Characterization of a chemically modified plant cell culture expressed human α-Galactosidase-A enzyme for treatment of Fabry disease.

Kizhner T, Azulay Y, Hainrichson M, Tekoah Y, Arvatz G, Shulman A, Ruderfer I, Aviezer D, Shaaltiel Y. Kizhner T, et al. Among authors: shaaltiel y. Mol Genet Metab. 2015 Feb;114(2):259-67. doi: 10.1016/j.ymgme.2014.08.002. Epub 2014 Aug 10. Mol Genet Metab. 2015. PMID: 25155442 Free article.

7

Plant specific N-glycans do not have proven adverse effects in humans.

Shaaltiel Y, Tekoah Y. Shaaltiel Y, et al. Nat Biotechnol. 2016 Jul 12;34(7):706-8. doi: 10.1038/nbt.3556. Nat Biotechnol. 2016. PMID: 27404878 No abstract available.

8

Development and Analytical Characterization of Pegunigalsidase Alfa, a Chemically Cross-Linked Plant Recombinant Human α-Galactosidase-A for Treatment of Fabry Disease.

Ruderfer I, Shulman A, Kizhner T, Azulay Y, Nataf Y, Tekoah Y, Shaaltiel Y. Ruderfer I, et al. Among authors: shaaltiel y. Bioconjug Chem. 2018 May 16;29(5):1630-1639. doi: 10.1021/acs.bioconjchem.8b00133. Epub 2018 May 3. Bioconjug Chem. 2018. PMID: 29698600

9

Sequential Genome Editing and Induced Excision of the Transgene in N. tabacum BY2 Cells.

Sheva M, Hanania U, Ariel T, Turbovski A, Rathod VKR, Oz D, Tekoah Y, Shaaltiel Y. Sheva M, et al. Among authors: shaaltiel y. Front Plant Sci. 2020 Nov 25;11:607174. doi: 10.3389/fpls.2020.607174. eCollection 2020. Front Plant Sci. 2020. PMID: 33324440 Free PMC article.

10

Preclinical and first-in-human evaluation of PRX-105, a PEGylated, plant-derived, recombinant human acetylcholinesterase-R.

Atsmon J, Brill-Almon E, Nadri-Shay C, Chertkoff R, Alon S, Shaikevich D, Volokhov I, Haim KY, Bartfeld D, Shulman A, Ruderfer I, Ben-Moshe T, Shilovitzky O, Soreq H, Shaaltiel Y. Atsmon J, et al. Among authors: shaaltiel y. Toxicol Appl Pharmacol. 2015 Sep 15;287(3):202-9. doi: 10.1016/j.taap.2015.06.004. Epub 2015 Jun 4. Toxicol Appl Pharmacol. 2015. PMID: 26051873 Clinical Trial.

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