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Increased susceptibility of ras-transformed cells to phenylacetate is associated with inhibition of p21ras isoprenylation and phenotypic reversion.
Shack S, Chen LC, Miller AC, Danesi R, Samid D. Shack S, et al. Int J Cancer. 1995 Sep 27;63(1):124-9. doi: 10.1002/ijc.2910630122. Int J Cancer. 1995. PMID: 7558439
Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate.
Shack S, Miller A, Liu L, Prasanna P, Thibault A, Samid D. Shack S, et al. Clin Cancer Res. 1996 May;2(5):865-72. Clin Cancer Res. 1996. PMID: 9816242 Free article.
Phenylacetate in chemoprevention: in vitro and in vivo suppression of 5-aza-2'-deoxycytidine-induced carcinogenesis.
Prasanna P, Shack S, Wilson VL, Samid D. Prasanna P, et al. Among authors: shack s. Clin Cancer Res. 1995 Aug;1(8):865-71. Clin Cancer Res. 1995. PMID: 9816056
Phenylacetate and phenylbutyrate as novel, nontoxic differentiation inducers.
Samid D, Hudgins WR, Shack S, Liu L, Prasanna P, Myers CE. Samid D, et al. Among authors: shack s. Adv Exp Med Biol. 1997;400A:501-5. doi: 10.1007/978-1-4615-5325-0_67. Adv Exp Med Biol. 1997. PMID: 9547596 Review.
Up-regulation and functional role of p21Waf1/Cip1 during growth arrest of human breast carcinoma MCF-7 cells by phenylacetate.
Gorospe M, Shack S, Guyton KZ, Samid D, Holbrook NJ. Gorospe M, et al. Among authors: shack s. Cell Growth Differ. 1996 Dec;7(12):1609-15. Cell Growth Differ. 1996. PMID: 8959328 Free article.
Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate.
Samid D, Shack S, Myers CE. Samid D, et al. Among authors: shack s. J Clin Invest. 1993 May;91(5):2288-95. doi: 10.1172/JCI116457. J Clin Invest. 1993. PMID: 8486788 Free PMC article.
Selective activity of phenylacetate against malignant gliomas: resemblance to fetal brain damage in phenylketonuria.
Samid D, Ram Z, Hudgins WR, Shack S, Liu L, Walbridge S, Oldfield EH, Myers CE. Samid D, et al. Among authors: shack s. Cancer Res. 1994 Feb 15;54(4):891-5. Cancer Res. 1994. PMID: 8313377
Growth inhibition, tumor maturation, and extended survival in experimental brain tumors in rats treated with phenylacetate.
Ram Z, Samid D, Walbridge S, Oshiro EM, Viola JJ, Tao-Cheng JH, Shack S, Thibault A, Myers CE, Oldfield EH. Ram Z, et al. Among authors: shack s. Cancer Res. 1994 Jun 1;54(11):2923-7. Cancer Res. 1994. PMID: 8187079
Differentiation of cultured human melanoma cells induced by the aromatic fatty acids phenylacetate and phenylbutyrate.
Liu L, Shack S, Stetler-Stevenson WG, Hudgins WR, Samid D. Liu L, et al. Among authors: shack s. J Invest Dermatol. 1994 Sep;103(3):335-40. doi: 10.1111/1523-1747.ep12394874. J Invest Dermatol. 1994. PMID: 8077698
Phenylacetate synergizes with retinoic acid in inducing the differentiation of human neuroblastoma cells.
Sidell N, Wada R, Han G, Chang B, Shack S, Moore T, Samid D. Sidell N, et al. Among authors: shack s. Int J Cancer. 1995 Feb 8;60(4):507-14. doi: 10.1002/ijc.2910600414. Int J Cancer. 1995. PMID: 7829265
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