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Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis.
Rodeheffer MS, Shadel GS. Rodeheffer MS, et al. J Biol Chem. 2003 May 16;278(20):18695-701. doi: 10.1074/jbc.M301399200. Epub 2003 Mar 10. J Biol Chem. 2003. PMID: 12637560 Free PMC article.
The conserved Mec1/Rad53 nuclear checkpoint pathway regulates mitochondrial DNA copy number in Saccharomyces cerevisiae.
Taylor SD, Zhang H, Eaton JS, Rodeheffer MS, Lebedeva MA, O'rourke TW, Siede W, Shadel GS. Taylor SD, et al. Mol Biol Cell. 2005 Jun;16(6):3010-8. doi: 10.1091/mbc.e05-01-0053. Epub 2005 Apr 13. Mol Biol Cell. 2005. PMID: 15829566 Free PMC article.
Transcription from the second heavy-strand promoter of human mtDNA is repressed by transcription factor A in vitro.
Lodeiro MF, Uchida A, Bestwick M, Moustafa IM, Arnold JJ, Shadel GS, Cameron CE. Lodeiro MF, et al. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6513-8. doi: 10.1073/pnas.1118710109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493245 Free PMC article.
Mitochondrial DNA oxidative damage and mutagenesis in Saccharomyces cerevisiae.
Griffiths LM, Doudican NA, Shadel GS, Doetsch PW. Griffiths LM, et al. Methods Mol Biol. 2009;554:267-86. doi: 10.1007/978-1-59745-521-3_17. Methods Mol Biol. 2009. PMID: 19513680
Oxidative DNA damage causes mitochondrial genomic instability in Saccharomyces cerevisiae.
Doudican NA, Song B, Shadel GS, Doetsch PW. Doudican NA, et al. Mol Cell Biol. 2005 Jun;25(12):5196-204. doi: 10.1128/MCB.25.12.5196-5204.2005. Mol Cell Biol. 2005. PMID: 15923634 Free PMC article.
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