Shadel GS - Search Results

1

Addition of a 29 residue carboxyl-terminal tail converts a simple HMG box-containing protein into a transcriptional activator.

Dairaghi DJ, Shadel GS, Clayton DA. Dairaghi DJ, et al. J Mol Biol. 1995 May 26;249(1):11-28. doi: 10.1006/jmbi.1995.9889. J Mol Biol. 1995. PMID: 7776365

2

Autoinducer-independent mutants of the LuxR transcriptional activator exhibit differential effects on the two lux promoters of Vibrio fischeri.

Sitnikov DM, Shadel GS, Baldwin TO. Sitnikov DM, et al. Mol Gen Genet. 1996 Oct 16;252(5):622-5. doi: 10.1007/BF02172408. Mol Gen Genet. 1996. PMID: 8914523

3

A novel mitochondrial protein, Tar1p, is encoded on the antisense strand of the nuclear 25S rDNA.

Coelho PS, Bryan AC, Kumar A, Shadel GS, Snyder M. Coelho PS, et al. Genes Dev. 2002 Nov 1;16(21):2755-60. doi: 10.1101/gad.1035002. Genes Dev. 2002. PMID: 12414727 Free PMC article.

4

Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis.

Rodeheffer MS, Shadel GS. Rodeheffer MS, et al. J Biol Chem. 2003 May 16;278(20):18695-701. doi: 10.1074/jbc.M301399200. Epub 2003 Mar 10. J Biol Chem. 2003. PMID: 12637560 Free PMC article.

5

Initiation and beyond: multiple functions of the human mitochondrial transcription machinery.

Bonawitz ND, Clayton DA, Shadel GS. Bonawitz ND, et al. Mol Cell. 2006 Dec 28;24(6):813-25. doi: 10.1016/j.molcel.2006.11.024. Mol Cell. 2006. PMID: 17189185 Review.

6

Defective mitochondrial gene expression results in reactive oxygen species-mediated inhibition of respiration and reduction of yeast life span.

Bonawitz ND, Rodeheffer MS, Shadel GS. Bonawitz ND, et al. Mol Cell Biol. 2006 Jul;26(13):4818-29. doi: 10.1128/MCB.02360-05. Mol Cell Biol. 2006. PMID: 16782871 Free PMC article.

7

The conserved Mec1/Rad53 nuclear checkpoint pathway regulates mitochondrial DNA copy number in Saccharomyces cerevisiae.

Taylor SD, Zhang H, Eaton JS, Rodeheffer MS, Lebedeva MA, O'rourke TW, Siede W, Shadel GS. Taylor SD, et al. Mol Biol Cell. 2005 Jun;16(6):3010-8. doi: 10.1091/mbc.e05-01-0053. Epub 2005 Apr 13. Mol Biol Cell. 2005. PMID: 15829566 Free PMC article.

8

Transcription from the second heavy-strand promoter of human mtDNA is repressed by transcription factor A in vitro.

Lodeiro MF, Uchida A, Bestwick M, Moustafa IM, Arnold JJ, Shadel GS, Cameron CE. Lodeiro MF, et al. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6513-8. doi: 10.1073/pnas.1118710109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493245 Free PMC article.

9

Mitochondrial DNA oxidative damage and mutagenesis in Saccharomyces cerevisiae.

Griffiths LM, Doudican NA, Shadel GS, Doetsch PW. Griffiths LM, et al. Methods Mol Biol. 2009;554:267-86. doi: 10.1007/978-1-59745-521-3_17. Methods Mol Biol. 2009. PMID: 19513680

10

Oxidative DNA damage causes mitochondrial genomic instability in Saccharomyces cerevisiae.

Doudican NA, Song B, Shadel GS, Doetsch PW. Doudican NA, et al. Mol Cell Biol. 2005 Jun;25(12):5196-204. doi: 10.1128/MCB.25.12.5196-5204.2005. Mol Cell Biol. 2005. PMID: 15923634 Free PMC article.

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