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Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram.
von Moltke LL, Greenblatt DJ, Giancarlo GM, Granda BW, Harmatz JS, Shader RI. von Moltke LL, et al. Among authors: shader ri. Drug Metab Dispos. 2001 Aug;29(8):1102-9. Drug Metab Dispos. 2001. PMID: 11454728
Bioinequivalence of a generic brand of diazepam.
Locniskar A, Greenblatt DJ, Harmatz JS, Shader RI. Locniskar A, et al. Among authors: shader ri. Biopharm Drug Dispos. 1989 Nov-Dec;10(6):597-605. doi: 10.1002/bdd.2510100609. Biopharm Drug Dispos. 1989. PMID: 2514810 Clinical Trial.
The effect of age on sildenafil biotransformation in rat and mouse liver microsomes.
Warrington JS, von Moltke LL, Harmatz JS, Shader RI, Greenblatt DJ. Warrington JS, et al. Among authors: shader ri. Drug Metab Dispos. 2003 Nov;31(11):1306-9. doi: 10.1124/dmd.31.11.1306. Drug Metab Dispos. 2003. PMID: 14570760
Pharmacokinetic properties of zolpidem in elderly and young adults: possible modulation by testosterone in men.
Olubodun JO, Ochs HR, von Moltke LL, Roubenoff R, Hesse LM, Harmatz JS, Shader RI, Greenblatt DJ. Olubodun JO, et al. Among authors: shader ri. Br J Clin Pharmacol. 2003 Sep;56(3):297-304. doi: 10.1046/j.0306-5251.2003.01852.x. Br J Clin Pharmacol. 2003. PMID: 12919178 Free PMC article. Clinical Trial.
Short-term exposure to low-dose ritonavir impairs clearance and enhances adverse effects of trazodone.
Greenblatt DJ, von Moltke LL, Harmatz JS, Fogelman SM, Chen G, Graf JA, Mertzanis P, Byron S, Culm KE, Granda BW, Daily JP, Shader RI. Greenblatt DJ, et al. Among authors: shader ri. J Clin Pharmacol. 2003 Apr;43(4):414-22. doi: 10.1177/0091270003251864. J Clin Pharmacol. 2003. PMID: 12723462 Clinical Trial.
In vitro biotransformation of sildenafil (Viagra) in the male rat: the role of CYP2C11.
Warrington JS, Von Moltke LL, Shader RI, Greenblatt DJ. Warrington JS, et al. Among authors: shader ri. Drug Metab Dispos. 2002 Jun;30(6):655-7. doi: 10.1124/dmd.30.6.655. Drug Metab Dispos. 2002. PMID: 12019191
Appetite suppressant drugs as inhibitors of human cytochromes P450: in vitro inhibition of P450-2D6 by D- and L-fenfluramine, but not phentermine.
von Moltke LL, Greenblatt DJ, Ciraulo DA, Grassi JM, Granda BW, Duan SX, Harmatz JS, Shader RI. von Moltke LL, et al. Among authors: shader ri. J Clin Psychopharmacol. 1998 Aug;18(4):338-41. doi: 10.1097/00004714-199808000-00015. J Clin Psychopharmacol. 1998. PMID: 9690701
Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: relation to pharmacokinetic interactions in vivo.
von Moltke LL, Greenblatt DJ, Duan SX, Harmatz JS, Wright CE, Shader RI. von Moltke LL, et al. Among authors: shader ri. J Clin Psychopharmacol. 1996 Apr;16(2):104-12. doi: 10.1097/00004714-199604000-00002. J Clin Psychopharmacol. 1996. PMID: 8690825
Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants.
von Moltke LL, Greenblatt DJ, Court MH, Duan SX, Harmatz JS, Shader RI. von Moltke LL, et al. Among authors: shader ri. J Clin Psychopharmacol. 1995 Apr;15(2):125-31. doi: 10.1097/00004714-199504000-00008. J Clin Psychopharmacol. 1995. PMID: 7782485
Human cytochromes mediating sertraline biotransformation: seeking attribution.
Greenblatt DJ, von Moltke LL, Harmatz JS, Shader RI. Greenblatt DJ, et al. Among authors: shader ri. J Clin Psychopharmacol. 1999 Dec;19(6):489-93. doi: 10.1097/00004714-199912000-00001. J Clin Psychopharmacol. 1999. PMID: 10587282 No abstract available.
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