Shader RI - Search Results

1

Enzyme kinetic modelling as a tool to analyse the behaviour of cytochrome P450 catalysed reactions: application to amitriptyline N-demethylation.

Schmider J, Greenblatt DJ, Harmatz JS, Shader RI. Schmider J, et al. Among authors: shader ri. Br J Clin Pharmacol. 1996 Jun;41(6):593-604. doi: 10.1046/j.1365-2125.1996.35717.x. Br J Clin Pharmacol. 1996. PMID: 8799527 Free PMC article.

2

Population study of triazolam pharmacokinetics.

Friedman H, Greenblatt DJ, Burstein ES, Harmatz JS, Shader RI. Friedman H, et al. Among authors: shader ri. Br J Clin Pharmacol. 1986 Dec;22(6):639-42. doi: 10.1111/j.1365-2125.1986.tb02951.x. Br J Clin Pharmacol. 1986. PMID: 3567010 Free PMC article.

3

Pharmocokinetics and pharmacodynamics of single-dose triazolam: electroencephalography compared with the Digit-Symbol Substitution Test.

Greenblatt DJ, Gan L, Harmatz JS, Shader RI. Greenblatt DJ, et al. Among authors: shader ri. Br J Clin Pharmacol. 2005 Sep;60(3):244-8. doi: 10.1111/j.1365-2125.2005.02409.x. Br J Clin Pharmacol. 2005. PMID: 16120062 Free PMC article. Clinical Trial.

4

Age and gender effects on the pharmacokinetics and pharmacodynamics of triazolam, a cytochrome P450 3A substrate.

Greenblatt DJ, Harmatz JS, von Moltke LL, Wright CE, Shader RI. Greenblatt DJ, et al. Among authors: shader ri. Clin Pharmacol Ther. 2004 Nov;76(5):467-79. doi: 10.1016/j.clpt.2004.07.009. Clin Pharmacol Ther. 2004. PMID: 15536461 Clinical Trial.

5

Kinetics and EEG effects of midazolam during and after 1-minute, 1-hour, and 3-hour intravenous infusions.

Greenblatt DJ, Ehrenberg BL, Culm KE, Scavone JM, Corbett KE, Friedman HL, Harmatz JS, Shader RI. Greenblatt DJ, et al. Among authors: shader ri. J Clin Pharmacol. 2004 Jun;44(6):605-11. doi: 10.1177/0091270004265368. J Clin Pharmacol. 2004. PMID: 15145968 Clinical Trial.

6

The effect of age on sildenafil biotransformation in rat and mouse liver microsomes.

Warrington JS, von Moltke LL, Harmatz JS, Shader RI, Greenblatt DJ. Warrington JS, et al. Among authors: shader ri. Drug Metab Dispos. 2003 Nov;31(11):1306-9. doi: 10.1124/dmd.31.11.1306. Drug Metab Dispos. 2003. PMID: 14570760

7

Pharmacokinetic properties of zolpidem in elderly and young adults: possible modulation by testosterone in men.

Olubodun JO, Ochs HR, von Moltke LL, Roubenoff R, Hesse LM, Harmatz JS, Shader RI, Greenblatt DJ. Olubodun JO, et al. Among authors: shader ri. Br J Clin Pharmacol. 2003 Sep;56(3):297-304. doi: 10.1046/j.0306-5251.2003.01852.x. Br J Clin Pharmacol. 2003. PMID: 12919178 Free PMC article. Clinical Trial.

8

Short-term exposure to low-dose ritonavir impairs clearance and enhances adverse effects of trazodone.

Greenblatt DJ, von Moltke LL, Harmatz JS, Fogelman SM, Chen G, Graf JA, Mertzanis P, Byron S, Culm KE, Granda BW, Daily JP, Shader RI. Greenblatt DJ, et al. Among authors: shader ri. J Clin Pharmacol. 2003 Apr;43(4):414-22. doi: 10.1177/0091270003251864. J Clin Pharmacol. 2003. PMID: 12723462 Clinical Trial.

9

In vitro biotransformation of sildenafil (Viagra) in the male rat: the role of CYP2C11.

Warrington JS, Von Moltke LL, Shader RI, Greenblatt DJ. Warrington JS, et al. Among authors: shader ri. Drug Metab Dispos. 2002 Jun;30(6):655-7. doi: 10.1124/dmd.30.6.655. Drug Metab Dispos. 2002. PMID: 12019191

10

Zolpidem pharmacokinetic properties in young females: influence of smoking and oral contraceptive use.

Olubodun JO, Ochs HR, Trüten V, Klein A, von Moltke LL, Harmatz JS, Shader RI, Greenblatt DJ. Olubodun JO, et al. Among authors: shader ri. J Clin Pharmacol. 2002 Oct;42(10):1142-6. doi: 10.1177/009127002401382623. J Clin Pharmacol. 2002. PMID: 12362929 Clinical Trial.

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