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Macrophage activation by heparanase is mediated by TLR-2 and TLR-4 and associates with plaque progression.
Blich M, Golan A, Arvatz G, Sebbag A, Shafat I, Sabo E, Cohen-Kaplan V, Petcherski S, Avniel-Polak S, Eitan A, Hammerman H, Aronson D, Axelman E, Ilan N, Nussbaum G, Vlodavsky I. Blich M, et al. Among authors: shafat i. Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):e56-65. doi: 10.1161/ATVBAHA.112.254961. Epub 2012 Nov 15. Arterioscler Thromb Vasc Biol. 2013. PMID: 23162016 Free PMC article.
An assay to evaluate heparanase procoagulant activity.
Nadir Y, Kenig Y, Drugan A, Shafat I, Brenner B. Nadir Y, et al. Among authors: shafat i. Thromb Res. 2011 Oct;128(4):e3-8. doi: 10.1016/j.thromres.2011.03.008. Epub 2011 Apr 8. Thromb Res. 2011. PMID: 21481923
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
Shafat I, Ben-Arush MW, Issakov J, Meller I, Naroditsky I, Tortoreto M, Cassinelli G, Lanzi C, Pisano C, Ilan N, Vlodavsky I, Zunino F. Shafat I, et al. J Cell Mol Med. 2011 Sep;15(9):1857-64. doi: 10.1111/j.1582-4934.2010.01190.x. J Cell Mol Med. 2011. PMID: 21029368 Free PMC article.
27 results