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Overloading and removal of N-glycosylation targets on human acetylcholinesterase: effects on glycan composition and circulatory residence time.
Chitlaru T, Kronman C, Velan B, Shafferman A. Chitlaru T, et al. Among authors: shafferman a. Biochem J. 2002 May 1;363(Pt 3):619-31. doi: 10.1042/0264-6021:3630619. Biochem J. 2002. PMID: 11964163 Free PMC article.
Optimization of post-translational modifications was shown to affect the ability of recombinant human acetylcholinesterase (rHuAChE) produced in HEK-293 cells to be retained in the circulation for prolonged periods of time [Kronman, Velan, Marcus, Ordentlich, Reuveny and Shaff …
Optimization of post-translational modifications was shown to affect the ability of recombinant human acetylcholinesterase (rHuAChE) produce …
Amino acid domains control the circulatory residence time of primate acetylcholinesterases in rhesus macaques (Macaca mulatta).
Cohen O, Kronman C, Velan B, Shafferman A. Cohen O, et al. Among authors: shafferman a. Biochem J. 2004 Feb 15;378(Pt 1):117-28. doi: 10.1042/BJ20031305. Biochem J. 2004. PMID: 14575524 Free PMC article.
The circulatory lifetimes of recombinant bovine, macaque and human AChEs in mice were governed by previously determined hierarchical rules; the longest circulatory residence time was obtained when AChE was fully sialylated and tetramerized [Kronman, Chitlaru, Elhanany, Velan and …
The circulatory lifetimes of recombinant bovine, macaque and human AChEs in mice were governed by previously determined hierarchical rules; …
167 results