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Early pathologic amyloid induces hypersynchrony of BOLD resting-state networks in transgenic mice and provides an early therapeutic window before amyloid plaque deposition.
Shah D, Praet J, Latif Hernandez A, Höfling C, Anckaerts C, Bard F, Morawski M, Detrez JR, Prinsen E, Villa A, De Vos WH, Maggi A, D'Hooge R, Balschun D, Rossner S, Verhoye M, Van der Linden A. Shah D, et al. Among authors: d hooge r. Alzheimers Dement. 2016 Sep;12(9):964-976. doi: 10.1016/j.jalz.2016.03.010. Epub 2016 Apr 21. Alzheimers Dement. 2016. PMID: 27107518
The autism- and schizophrenia-associated protein CYFIP1 regulates bilateral brain connectivity and behaviour.
Domínguez-Iturza N, Lo AC, Shah D, Armendáriz M, Vannelli A, Mercaldo V, Trusel M, Li KW, Gastaldo D, Santos AR, Callaerts-Vegh Z, D'Hooge R, Mameli M, Van der Linden A, Smit AB, Achsel T, Bagni C. Domínguez-Iturza N, et al. Among authors: d hooge r, shah d. Nat Commun. 2019 Aug 1;10(1):3454. doi: 10.1038/s41467-019-11203-y. Nat Commun. 2019. PMID: 31371726 Free PMC article.
Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease.
Shah D, Gsell W, Wahis J, Luckett ES, Jamoulle T, Vermaercke B, Preman P, Moechars D, Hendrickx V, Jaspers T, Craessaerts K, Horré K, Wolfs L, Fiers M, Holt M, Thal DR, Callaerts-Vegh Z, D'Hooge R, Vandenberghe R, Himmelreich U, Bonin V, De Strooper B. Shah D, et al. Among authors: d hooge r. Cell Rep. 2022 Aug 23;40(8):111280. doi: 10.1016/j.celrep.2022.111280. Cell Rep. 2022. PMID: 36001964 Free PMC article.
3,628 results