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3,197 results
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A chemical genetic screen for direct v-Src substrates reveals ordered assembly of a retrograde signaling pathway.
Shah K, Shokat KM. Shah K, et al. Chem Biol. 2002 Jan;9(1):35-47. doi: 10.1016/s1074-5521(02)00086-8. Chem Biol. 2002. PMID: 11841937
Engineering unnatural nucleotide specificity to probe G protein signaling.
Vincent F, Cook SP, Johnson EO, Emmert D, Shah K. Vincent F, et al. Among authors: shah k. Chem Biol. 2007 Sep;14(9):1007-18. doi: 10.1016/j.chembiol.2007.08.006. Chem Biol. 2007. PMID: 17884633
Identification of ChChd3 as a novel substrate of the cAMP-dependent protein kinase (PKA) using an analog-sensitive catalytic subunit.
Schauble S, King CC, Darshi M, Koller A, Shah K, Taylor SS. Schauble S, et al. Among authors: shah k. J Biol Chem. 2007 May 18;282(20):14952-9. doi: 10.1074/jbc.M609221200. Epub 2007 Jan 22. J Biol Chem. 2007. PMID: 17242405
A chemical genetic approach for the identification of direct substrates of protein kinases.
Shah K, Shokat KM. Shah K, et al. Methods Mol Biol. 2003;233:253-71. doi: 10.1385/1-59259-397-6:253. Methods Mol Biol. 2003. PMID: 12840513 No abstract available.
Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs.
Eblen ST, Kumar NV, Shah K, Henderson MJ, Watts CK, Shokat KM, Weber MJ. Eblen ST, et al. Among authors: shah k. J Biol Chem. 2003 Apr 25;278(17):14926-35. doi: 10.1074/jbc.M300485200. Epub 2003 Feb 19. J Biol Chem. 2003. PMID: 12594221
Mutant tyrosine kinases with unnatural nucleotide specificity retain the structure and phospho-acceptor specificity of the wild-type enzyme.
Witucki LA, Huang X, Shah K, Liu Y, Kyin S, Eck MJ, Shokat KM. Witucki LA, et al. Among authors: shah k. Chem Biol. 2002 Jan;9(1):25-33. doi: 10.1016/s1074-5521(02)00091-1. Chem Biol. 2002. PMID: 11841936
Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue.
Habelhah H, Shah K, Huang L, Burlingame AL, Shokat KM, Ronai Z. Habelhah H, et al. Among authors: shah k. J Biol Chem. 2001 May 25;276(21):18090-5. doi: 10.1074/jbc.M011396200. Epub 2001 Mar 19. J Biol Chem. 2001. PMID: 11259409
A molecular gate which controls unnatural ATP analogue recognition by the tyrosine kinase v-Src.
Liu Y, Shah K, Yang F, Witucki L, Shokat KM. Liu Y, et al. Among authors: shah k. Bioorg Med Chem. 1998 Aug;6(8):1219-26. doi: 10.1016/s0968-0896(98)00099-6. Bioorg Med Chem. 1998. PMID: 9784863
Design of allele-specific inhibitors to probe protein kinase signaling.
Bishop AC, Shah K, Liu Y, Witucki L, Kung C, Shokat KM. Bishop AC, et al. Among authors: shah k. Curr Biol. 1998 Feb 26;8(5):257-66. doi: 10.1016/s0960-9822(98)70198-8. Curr Biol. 1998. PMID: 9501066
Engineering unnatural nucleotide specificity for Rous sarcoma virus tyrosine kinase to uniquely label its direct substrates.
Shah K, Liu Y, Deirmengian C, Shokat KM. Shah K, et al. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3565-70. doi: 10.1073/pnas.94.8.3565. Proc Natl Acad Sci U S A. 1997. PMID: 9108016 Free PMC article.
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