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RasGRP1 is a causal factor in the development of l-DOPA-induced dyskinesia in Parkinson's disease.
Eshraghi M, Ramírez-Jarquín UN, Shahani N, Nuzzo T, De Rosa A, Swarnkar S, Galli N, Rivera O, Tsaprailis G, Scharager-Tapia C, Crynen G, Li Q, Thiolat ML, Bezard E, Usiello A, Subramaniam S. Eshraghi M, et al. Among authors: shahani n. Sci Adv. 2020 May 1;6(18):eaaz7001. doi: 10.1126/sciadv.aaz7001. eCollection 2020 May. Sci Adv. 2020. PMID: 32426479 Free PMC article.
Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade.
Tyagi R, Shahani N, Gorgen L, Ferretti M, Pryor W, Chen PY, Swarnkar S, Worley PF, Karbstein K, Snyder SH, Subramaniam S. Tyagi R, et al. Among authors: shahani n. Cell Rep. 2015 Feb 10;10(5):684-693. doi: 10.1016/j.celrep.2015.01.014. Epub 2015 Feb 7. Cell Rep. 2015. PMID: 25660019 Free PMC article.
Rhes, a striatal-enriched protein, promotes mitophagy via Nix.
Sharma M, Ramírez Jarquín UN, Rivera O, Kazantzis M, Eshraghi M, Shahani N, Sharma V, Tapia R, Subramaniam S. Sharma M, et al. Among authors: shahani n. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23760-23771. doi: 10.1073/pnas.1912868116. Epub 2019 Nov 1. Proc Natl Acad Sci U S A. 2019. PMID: 31676548 Free PMC article.
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis.
Sen N, Hara MR, Kornberg MD, Cascio MB, Bae BI, Shahani N, Thomas B, Dawson TM, Dawson VL, Snyder SH, Sawa A. Sen N, et al. Among authors: shahani n. Nat Cell Biol. 2008 Jul;10(7):866-73. doi: 10.1038/ncb1747. Epub 2008 Jun 15. Nat Cell Biol. 2008. PMID: 18552833 Free PMC article.
Global Rhes knockout in the Q175 Huntington's disease mouse model.
Heikkinen T, Bragge T, Kuosmanen J, Parkkari T, Gustafsson S, Kwan M, Beltran J, Ghavami A, Subramaniam S, Shahani N, Ramírez-Jarquín UN, Park L, Muñoz-Sanjuán I, Marchionini DM. Heikkinen T, et al. Among authors: shahani n. PLoS One. 2021 Oct 14;16(10):e0258486. doi: 10.1371/journal.pone.0258486. eCollection 2021. PLoS One. 2021. PMID: 34648564 Free PMC article.
42 results