Sham YY - Search Results

1

N-3 Hydroxylation of Pyrimidine-2,4-diones Yields Dual Inhibitors of HIV Reverse Transcriptase and Integrase.

Tang J, Maddali K, Dreis CD, Sham YY, Vince R, Pommier Y, Wang Z. Tang J, et al. Among authors: sham yy. ACS Med Chem Lett. 2011 Jan;2(1):63-67. doi: 10.1021/ml1002162. ACS Med Chem Lett. 2011. PMID: 21499541 Free PMC article.

2

Design and synthesis of sulfoximine based inhibitors for HIV-1 protease.

Raza A, Sham YY, Vince R. Raza A, et al. Among authors: sham yy. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5406-10. doi: 10.1016/j.bmcl.2008.09.044. Epub 2008 Sep 13. Bioorg Med Chem Lett. 2008. PMID: 18829317

3

Design, asymmetric synthesis, and evaluation of pseudosymmetric sulfoximine inhibitors against HIV-1 protease.

Lu D, Sham YY, Vince R. Lu D, et al. Among authors: sham yy. Bioorg Med Chem. 2010 Mar 1;18(5):2037-48. doi: 10.1016/j.bmc.2010.01.020. Epub 2010 Jan 21. Bioorg Med Chem. 2010. PMID: 20138769

4

Scaffold rearrangement of dihydroxypyrimidine inhibitors of HIV integrase: Docking model revisited.

Tang J, Maddali K, Pommier Y, Sham YY, Wang Z. Tang J, et al. Among authors: sham yy. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3275-9. doi: 10.1016/j.bmcl.2010.04.048. Epub 2010 Apr 21. Bioorg Med Chem Lett. 2010. PMID: 20457521 Free PMC article.

5

Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis.

Chen L, Wilson DJ, Xu Y, Aldrich CC, Felczak K, Sham YY, Pankiewicz KW. Chen L, et al. Among authors: sham yy. J Med Chem. 2010 Jun 24;53(12):4768-78. doi: 10.1021/jm100424m. J Med Chem. 2010. PMID: 20491506 Free PMC article.

6

3-Hydroxypyrimidine-2,4-diones as an inhibitor scaffold of HIV integrase.

Tang J, Maddali K, Metifiot M, Sham YY, Vince R, Pommier Y, Wang Z. Tang J, et al. Among authors: sham yy. J Med Chem. 2011 Apr 14;54(7):2282-92. doi: 10.1021/jm1014378. Epub 2011 Mar 7. J Med Chem. 2011. PMID: 21381765 Free PMC article.

7

6-Benzoyl-3-hydroxypyrimidine-2,4-diones as dual inhibitors of HIV reverse transcriptase and integrase.

Tang J, Maddali K, Dreis CD, Sham YY, Vince R, Pommier Y, Wang Z. Tang J, et al. Among authors: sham yy. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2400-2. doi: 10.1016/j.bmcl.2011.02.069. Epub 2011 Feb 18. Bioorg Med Chem Lett. 2011. PMID: 21392991 Free PMC article.

8

The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus.

Chen YL, Tang J, Kesler MJ, Sham YY, Vince R, Geraghty RJ, Wang Z. Chen YL, et al. Among authors: sham yy. Bioorg Med Chem. 2012 Jan 1;20(1):467-79. doi: 10.1016/j.bmc.2011.10.058. Epub 2011 Oct 24. Bioorg Med Chem. 2012. PMID: 22100256

9

5-Arylidenethioxothiazolidinones as inhibitors of tyrosyl-DNA phosphodiesterase I.

Sirivolu VR, Vernekar SK, Marchand C, Naumova A, Chergui A, Renaud A, Stephen AG, Chen F, Sham YY, Pommier Y, Wang Z. Sirivolu VR, et al. Among authors: sham yy. J Med Chem. 2012 Oct 25;55(20):8671-84. doi: 10.1021/jm3008773. Epub 2012 Oct 8. J Med Chem. 2012. PMID: 23006064 Free PMC article.

10

Rapid identification of Keap1-Nrf2 small-molecule inhibitors through structure-based virtual screening and hit-based substructure search.

Zhuang C, Narayanapillai S, Zhang W, Sham YY, Xing C. Zhuang C, et al. Among authors: sham yy. J Med Chem. 2014 Feb 13;57(3):1121-6. doi: 10.1021/jm4017174. Epub 2014 Jan 17. J Med Chem. 2014. PMID: 24417449

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