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Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins.
Hardwick JS, Kuruvilla FG, Tong JK, Shamji AF, Schreiber SL. Hardwick JS, et al. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14866-70. doi: 10.1073/pnas.96.26.14866. Proc Natl Acad Sci U S A. 1999. PMID: 10611304 Free PMC article.
Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules.
Shaw SY, Tran K, Castoreno AB, Peloquin JM, Lassen KG, Khor B, Aldrich LN, Tan PH, Graham DB, Kuballa P, Goel G, Daly MJ, Shamji AF, Schreiber SL, Xavier RJ. Shaw SY, et al. ACS Chem Biol. 2013 Dec 20;8(12):2724-2733. doi: 10.1021/cb400352d. Epub 2013 Oct 29. ACS Chem Biol. 2013. PMID: 24168452 Free PMC article.
Rpd3p relocation mediates a transcriptional response to rapamycin in yeast.
Humphrey EL, Shamji AF, Bernstein BE, Schreiber SL. Humphrey EL, et al. Chem Biol. 2004 Mar;11(3):295-9. doi: 10.1016/j.chembiol.2004.03.001. Chem Biol. 2004. PMID: 15123258
Small-molecule control of cytokine function: new opportunities for treating immune disorders.
Sundberg TB, Xavier RJ, Schreiber SL, Shamji AF. Sundberg TB, et al. Curr Opin Chem Biol. 2014 Dec;23:23-30. doi: 10.1016/j.cbpa.2014.08.013. Epub 2014 Sep 15. Curr Opin Chem Biol. 2014. PMID: 25222143 Free PMC article. Review.
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