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TL1A/TNFSF15 directly induces proinflammatory cytokines, including TNFα, from CD3+CD161+ T cells to exacerbate gut inflammation.
Jin S, Chin J, Seeber S, Niewoehner J, Weiser B, Beaucamp N, Woods J, Murphy C, Fanning A, Shanahan F, Nally K, Kajekar R, Salas A, Planell N, Lozano J, Panes J, Parmar H, DeMartino J, Narula S, Thomas-Karyat DA. Jin S, et al. Among authors: shanahan f. Mucosal Immunol. 2013 Sep;6(5):886-99. doi: 10.1038/mi.2012.124. Epub 2012 Dec 19. Mucosal Immunol. 2013. PMID: 23250276 Free article.
Shining a light on intestinal traffic.
Murphy CT, Nally K, Shanahan F, Melgar S. Murphy CT, et al. Among authors: shanahan f. Clin Dev Immunol. 2012;2012:808157. doi: 10.1155/2012/808157. Epub 2011 Nov 22. Clin Dev Immunol. 2012. PMID: 22162719 Free PMC article. Review.
Down-regulation of p38 mitogen-activated protein kinase activation and proinflammatory cytokine production by mitogen-activated protein kinase inhibitors in inflammatory bowel disease.
Docena G, Rovedatti L, Kruidenier L, Fanning A, Leakey NA, Knowles CH, Lee K, Shanahan F, Nally K, McLean PG, Di Sabatino A, MacDonald TT. Docena G, et al. Among authors: shanahan f. Clin Exp Immunol. 2010 Oct;162(1):108-15. doi: 10.1111/j.1365-2249.2010.04203.x. Epub 2010 Aug 20. Clin Exp Immunol. 2010. PMID: 20731675 Free PMC article.
Regulation of CEACAM Family Members by IBD-Associated Triggers in Intestinal Epithelial Cells, Their Correlation to Inflammation and Relevance to IBD Pathogenesis.
Saiz-Gonzalo G, Hanrahan N, Rossini V, Singh R, Ahern M, Kelleher M, Hill S, O'Sullivan R, Fanning A, Walsh PT, Hussey S, Shanahan F, Nally K, O'Driscoll CM, Melgar S. Saiz-Gonzalo G, et al. Among authors: shanahan f. Front Immunol. 2021 Jul 29;12:655960. doi: 10.3389/fimmu.2021.655960. eCollection 2021. Front Immunol. 2021. PMID: 34394073 Free PMC article.
Human BCL-G regulates secretion of inflammatory chemokines but is dispensable for induction of apoptosis by IFN-γ and TNF-α in intestinal epithelial cells.
Woznicki JA, Flood P, Bustamante-Garrido M, Stamou P, Moloney G, Fanning A, Zulquernain SA, McCarthy J, Shanahan F, Melgar S, Nally K. Woznicki JA, et al. Among authors: shanahan f. Cell Death Dis. 2020 Jan 27;11(1):68. doi: 10.1038/s41419-020-2263-0. Cell Death Dis. 2020. PMID: 31988296 Free PMC article.
Turning on T-cell death and turning off Crohn's disease.
Shanahan F, Nally K, O'Sullivan GC. Shanahan F, et al. Gastroenterology. 2000 Oct;119(4):1166-8. doi: 10.1016/s0016-5085(00)80035-9. Gastroenterology. 2000. PMID: 11040205 No abstract available.
627 results