Shank RP - Search Results

1

Topiramate monotherapy in epilepsy and migraine prevention.

Silberstein SD, Ben-Menachem E, Shank RP, Wiegand F. Silberstein SD, et al. Among authors: shank rp. Clin Ther. 2005 Feb;27(2):154-65. doi: 10.1016/j.clinthera.2005.02.013. Clin Ther. 2005. PMID: 15811478 Review.

2

Anticonvulsant activity of topiramate and phenytoin in a rat model of ischemia-induced epilepsy.

Edmonds HL Jr, Jiang YD, Zhang PY, Shank RP. Edmonds HL Jr, et al. Among authors: shank rp. Life Sci. 1996;59(10):PL127-31. doi: 10.1016/0024-3205(96)00379-7. Life Sci. 1996. PMID: 8761322

3

In vivo microdialysis and liquid chromatography/thermospray mass spectrometry of the novel anticonvulsant 2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate (topiramate) in rat brain fluid.

Masucci JA, Ortegon ME, Jones WJ, Shank RP, Caldwell GW. Masucci JA, et al. Among authors: shank rp. J Mass Spectrom. 1998 Jan;33(1):85-8. doi: 10.1002/(SICI)1096-9888(199801)33:1<85::AID-JMS612>3.0.CO;2-R. J Mass Spectrom. 1998. PMID: 9449831

4

An overview of the preclinical aspects of topiramate: pharmacology, pharmacokinetics, and mechanism of action.

Shank RP, Gardocki JF, Streeter AJ, Maryanoff BE. Shank RP, et al. Epilepsia. 2000;41(S1):3-9. Epilepsia. 2000. PMID: 10768292 Free article. Review.

5

Molecular pharmacodynamics, clinical therapeutics, and pharmacokinetics of topiramate.

Shank RP, Maryanoff BE. Shank RP, et al. CNS Neurosci Ther. 2008 Summer;14(2):120-42. doi: 10.1111/j.1527-3458.2008.00041.x. CNS Neurosci Ther. 2008. PMID: 18482025 Free PMC article. Review.

6

Plasma and whole blood pharmacokinetics of topiramate: the role of carbonic anhydrase.

Shank RP, Doose DR, Streeter AJ, Bialer M. Shank RP, et al. Epilepsy Res. 2005 Feb;63(2-3):103-12. doi: 10.1016/j.eplepsyres.2005.01.001. Epilepsy Res. 2005. PMID: 15715969 Clinical Trial.

7

Comparison of sulfamate and sulfamide groups for the inhibition of carbonic anhydrase-II by using topiramate as a structural platform.

Maryanoff BE, McComsey DF, Costanzo MJ, Hochman C, Smith-Swintosky V, Shank RP. Maryanoff BE, et al. Among authors: shank rp. J Med Chem. 2005 Mar 24;48(6):1941-7. doi: 10.1021/jm040124c. J Med Chem. 2005. PMID: 15771438

8

Structure-activity studies on anticonvulsant sugar sulfamates related to topiramate. Enhanced potency with cyclic sulfate derivatives.

Maryanoff BE, Costanzo MJ, Nortey SO, Greco MN, Shank RP, Schupsky JJ, Ortegon MP, Vaught JL. Maryanoff BE, et al. Among authors: shank rp. J Med Chem. 1998 Apr 9;41(8):1315-43. doi: 10.1021/jm970790w. J Med Chem. 1998. PMID: 9548821

9

Topiramate as a neuroprotectant in a rat model of global ischemia-induced neurodegeneration.

Edmonds HL Jr, Jiang YD, Zhang PY, Shank R. Edmonds HL Jr, et al. Life Sci. 2001 Sep 28;69(19):2265-77. doi: 10.1016/s0024-3205(01)01306-6. Life Sci. 2001. PMID: 11669469

10

Topiramate: preclinical evaluation of structurally novel anticonvulsant.

Shank RP, Gardocki JF, Vaught JL, Davis CB, Schupsky JJ, Raffa RB, Dodgson SJ, Nortey SO, Maryanoff BE. Shank RP, et al. Epilepsia. 1994 Mar-Apr;35(2):450-60. doi: 10.1111/j.1528-1157.1994.tb02459.x. Epilepsia. 1994. PMID: 8156972

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