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MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma.
Roy SK, Hu J, Meng Q, Xia Y, Shapiro PS, Reddy SP, Platanias LC, Lindner DJ, Johnson PF, Pritchard C, Pagés G, Pouyssegur J, Kalvakolanu DV. Roy SK, et al. Among authors: shapiro ps. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):7945-50. doi: 10.1073/pnas.122075799. Epub 2002 Jun 4. Proc Natl Acad Sci U S A. 2002. PMID: 12048245 Free PMC article.
Involvement of the MAP kinase ERK2 in MUC1 mucin signaling.
Meerzaman D, Shapiro PS, Kim KC. Meerzaman D, et al. Among authors: shapiro ps. Am J Physiol Lung Cell Mol Physiol. 2001 Jul;281(1):L86-91. doi: 10.1152/ajplung.2001.281.1.L86. Am J Physiol Lung Cell Mol Physiol. 2001. PMID: 11404250
Development of extracellular signal-regulated kinase inhibitors.
Burkhard K, Smith S, Deshmukh R, MacKerell AD Jr, Shapiro P. Burkhard K, et al. Among authors: shapiro p. Curr Top Med Chem. 2009;9(8):678-89. doi: 10.2174/156802609789044416. Curr Top Med Chem. 2009. PMID: 19689374 Free PMC article. Review.
Use of inhibitors in the study of MAP kinases.
Burkhard K, Shapiro P. Burkhard K, et al. Among authors: shapiro p. Methods Mol Biol. 2010;661:107-22. doi: 10.1007/978-1-60761-795-2_6. Methods Mol Biol. 2010. PMID: 20811979 Free PMC article.
Structure of extracellular signal-regulated kinase 2 in complex with ATP and ADP.
Zhang J, Shapiro P, Pozharski E. Zhang J, et al. Among authors: shapiro p. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1434-9. doi: 10.1107/S1744309112042972. Epub 2012 Nov 14. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 23192020 Free PMC article.
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