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Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.
van 't Hof FN, Ruigrok YM, Lee CH, Ripke S, Anderson G, de Andrade M, Baas AF, Blankensteijn JD, Böttinger EP, Bown MJ, Broderick J, Bijlenga P, Carrell DS, Crawford DC, Crosslin DR, Ebeling C, Eriksson JG, Fornage M, Foroud T, von Und Zu Fraunberg M, Friedrich CM, Gaál EI, Gottesman O, Guo DC, Harrison SC, Hernesniemi J, Hofman A, Inoue I, Jääskeläinen JE, Jones GT, Kiemeney LA, Kivisaari R, Ko N, Koskinen S, Kubo M, Kullo IJ, Kuivaniemi H, Kurki MI, Laakso A, Lai D, Leal SM, Lehto H, LeMaire SA, Low SK, Malinowski J, McCarty CA, Milewicz DM, Mosley TH, Nakamura Y, Nakaoka H, Niemelä M, Pacheco J, Peissig PL, Pera J, Rasmussen-Torvik L, Ritchie MD, Rivadeneira F, van Rij AM, Santos-Cortez RL, Saratzis A, Slowik A, Takahashi A, Tromp G, Uitterlinden AG, Verma SS, Vermeulen SH, Wang GT; Aneurysm Consortium; Vascular Research Consortium of New Zealand; Han B, Rinkel GJ, de Bakker PI. van 't Hof FN, et al. J Am Heart Assoc. 2016 Jul 14;5(7):e002603. doi: 10.1161/JAHA.115.002603. J Am Heart Assoc. 2016. PMID: 27418160 Free PMC article.
BACKGROUND: Intracranial aneurysms (IAs), abdominal aortic aneurysms (AAAs), and thoracic aortic aneurysms (TAAs) all have a familial predisposition. Given that aneurysm types are known to co-occur, we hypothesized that there may b …
BACKGROUND: Intracranial aneurysms (IAs), abdominal aortic aneurysms (AAAs), and thoracic aortic aneur
Comparative Analysis of Circular RNAs Expression and Function between Aortic and Intracranial Aneurysms.
Gareev I, Beylerli O, Ahmad A, Ilyasova T, Shi H, Chekhonin V. Gareev I, et al. Curr Drug Targets. 2024;25(13):866-884. doi: 10.2174/0113894501319306240819052840. Curr Drug Targets. 2024. PMID: 39219419 Free PMC article. Review.
An aneurysm is an abnormal enlargement or bulging of the wall of a blood vessel. Most often, aneurysms occur in large blood vessels - the aorta (Thoracic Aortic Aneurysm (TAA) and Abdominal Aortic Aneurysm (AAA)) and brain vessels (Int
An aneurysm is an abnormal enlargement or bulging of the wall of a blood vessel. Most often, aneurysms occur in large blood ve …
Family history as the strongest predictor of aortic and peripheral aneurysms in patients with intracranial aneurysms.
Lai PMR, Akama-Garren E, Can A, Tirado SR, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R. Lai PMR, et al. J Clin Neurosci. 2024 Aug;126:128-134. doi: 10.1016/j.jocn.2024.05.041. Epub 2024 Jun 12. J Clin Neurosci. 2024. PMID: 38870642
Associations of IA and non-aortic peripheral aneurysms are less well-studied. The goal of the study was to understand the patterns of aortic and peripheral (extracranial) aneurysms in patients with IA, and risk factors associated with the development o …
Associations of IA and non-aortic peripheral aneurysms are less well-studied. The goal of the study was to understand the patterns of …