Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk Estimates: Effect on Low-Density Lipoprotein Cholesterol Levels (the MI-GENES Clinical Trial).
Kullo IJ, Jouni H, Austin EE, Brown SA, Kruisselbrink TM, Isseh IN, Haddad RA, Marroush TS, Shameer K, Olson JE, Broeckel U, Green RC, Schaid DJ, Montori VM, Bailey KR.
Kullo IJ, et al.
Circulation. 2016 Mar 22;133(12):1181-8. doi: 10.1161/CIRCULATIONAHA.115.020109. Epub 2016 Feb 25.
Circulation. 2016.
PMID: 26915630
Free PMC article.
Clinical Trial.
BACKGROUND: Whether knowledge of genetic risk for coronary heart disease (CHD) affects health-related outcomes is unknown. ...Participants in the (+)GRS group were stratified as having high or average/low GRS. Risk was disclosed by a g …
BACKGROUND: Whether knowledge of genetic risk for coronary heart disease (CHD) affects health-related out …