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Discovery and Optimization of a Series of Pyrimidine-Based Phosphodiesterase 10A (PDE10A) Inhibitors through Fragment Screening, Structure-Based Design, and Parallel Synthesis.
J Med Chem. 2015 Oct 8;58(19):7888-94. doi: 10.1021/acs.jmedchem.5b00983. Epub 2015 Sep 25.
J Med Chem. 2015.
PMID: 26378882
Identification of potent, highly constrained CGRP receptor antagonists.
Stump CA, Bell IM, Bednar RA, Fay JF, Gallicchio SN, Hershey JC, Jelley R, Kreatsoulas C, Moore EL, Mosser SD, Quigley AG, Roller SA, Salvatore CA, Sharik SS, Theberge CR, Zartman CB, Kane SA, Graham SL, Selnick HG, Vacca JP, Williams TM.
Stump CA, et al. Among authors: sharik ss.
Bioorg Med Chem Lett. 2010 Apr 15;20(8):2572-6. doi: 10.1016/j.bmcl.2010.02.086. Epub 2010 Feb 25.
Bioorg Med Chem Lett. 2010.
PMID: 20299218
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Inhibition of glycine transporter 1 attenuates nicotine- but not food-induced cue-potentiated reinstatement for a response previously paired with sucrose.
Uslaner JM, Drott JT, Sharik SS, Theberge CR, Sur C, Zeng Z, Williams DL, Hutson PH.
Uslaner JM, et al. Among authors: sharik ss.
Behav Brain Res. 2010 Feb 11;207(1):37-43. doi: 10.1016/j.bbr.2009.09.035. Epub 2009 Sep 30.
Behav Brain Res. 2010.
PMID: 19799936
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Total synthesis of (-)-normalindine via addition of metalated 4-methyl-3-cyanopyridine to an enantiopure sulfinimine.
Davis FA, Melamed JY, Sharik SS.
Davis FA, et al. Among authors: sharik ss.
J Org Chem. 2006 Nov 10;71(23):8761-6. doi: 10.1021/jo061443+.
J Org Chem. 2006.
PMID: 17081004
Free PMC article.
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