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7,752 results
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Prediction of the in vivo OATP1B1-mediated drug-drug interaction potential of an investigational drug against a range of statins.
Sharma P, Butters CJ, Smith V, Elsby R, Surry D. Sharma P, et al. Eur J Pharm Sci. 2012 Aug 30;47(1):244-55. doi: 10.1016/j.ejps.2012.04.003. Epub 2012 Apr 19. Eur J Pharm Sci. 2012. PMID: 22538052
Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin Exposure.
Elsby R, Martin P, Surry D, Sharma P, Fenner K. Elsby R, et al. Among authors: sharma p. Drug Metab Dispos. 2016 Mar;44(3):398-408. doi: 10.1124/dmd.115.066795. Epub 2015 Dec 23. Drug Metab Dispos. 2016. PMID: 26700956
Validation of membrane vesicle-based breast cancer resistance protein and multidrug resistance protein 2 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.
Elsby R, Smith V, Fox L, Stresser D, Butters C, Sharma P, Surry DD. Elsby R, et al. Among authors: sharma p. Xenobiotica. 2011 Sep;41(9):764-83. doi: 10.3109/00498254.2011.578761. Epub 2011 May 25. Xenobiotica. 2011. PMID: 21612343
The utility of in vitro data in making accurate predictions of human P-glycoprotein-mediated drug-drug interactions: a case study for AZD5672.
Elsby R, Gillen M, Butters C, Imisson G, Sharma P, Smith V, Surry DD. Elsby R, et al. Among authors: sharma p. Drug Metab Dispos. 2011 Feb;39(2):275-82. doi: 10.1124/dmd.110.035881. Epub 2010 Nov 12. Drug Metab Dispos. 2011. PMID: 21075975 Clinical Trial.
In vitro risk assessment of AZD9056 perpetrating a transporter-mediated drug-drug interaction with methotrexate.
Elsby R, Fox L, Stresser D, Layton M, Butters C, Sharma P, Smith V, Surry D. Elsby R, et al. Among authors: sharma p. Eur J Pharm Sci. 2011 May 18;43(1-2):41-9. doi: 10.1016/j.ejps.2011.03.006. Epub 2011 Apr 1. Eur J Pharm Sci. 2011. PMID: 21440623
Validation of cell-based OATP1B1 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.
Sharma P, Holmes VE, Elsby R, Lambert C, Surry D. Sharma P, et al. Xenobiotica. 2010 Jan;40(1):24-37. doi: 10.3109/00498250903351013. Xenobiotica. 2010. PMID: 19919292
Design, synthesis, in vitro characterization and preliminary imaging studies on fluorinated bile acid derivatives as PET tracers to study hepatic transporters.
Testa A, Dall'Angelo S, Mingarelli M, Augello A, Schweiger L, Welch A, Elmore CS, Sharma P, Zanda M. Testa A, et al. Among authors: sharma p. Bioorg Med Chem. 2017 Feb 1;25(3):963-976. doi: 10.1016/j.bmc.2016.12.008. Epub 2016 Dec 9. Bioorg Med Chem. 2017. PMID: 28011201
Development, Verification, and Prediction of Osimertinib Drug-Drug Interactions Using PBPK Modeling Approach to Inform Drug Label.
Pilla Reddy V, Walker M, Sharma P, Ballard P, Vishwanathan K. Pilla Reddy V, et al. Among authors: sharma p. CPT Pharmacometrics Syst Pharmacol. 2018 May;7(5):321-330. doi: 10.1002/psp4.12289. Epub 2018 Mar 15. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 29468841 Free PMC article.
Preclinical Evaluation of [18F]LCATD as a PET Tracer to Study Drug-Drug Interactions Caused by Inhibition of Hepatic Transporters.
Testa A, Dall'Angelo S, Mingarelli M, Augello A, Schweiger L, Welch A, Elmore CS, Dawson D, Sharma P, Zanda M. Testa A, et al. Among authors: sharma p. Contrast Media Mol Imaging. 2018 Jul 30;2018:3064751. doi: 10.1155/2018/3064751. eCollection 2018. Contrast Media Mol Imaging. 2018. PMID: 30154685 Free PMC article.
Hypoxia-inducible factor (HIF): fuel for cancer progression.
Satija S, Kaur H, Tambuwala MM, Sharma P, Vyas M, Khurana N, Sharma N, Bakshi HA, Charbe NB, Zacconi FC, Aljabali AA, Nammi S, Dureja H, Singh TG, Gupta G, Dhanjal DS, Dua K, Chellappan DK, Mehta M. Satija S, et al. Among authors: sharma p. Curr Mol Pharmacol. 2021 Jan 20. doi: 10.2174/1874467214666210120154929. Online ahead of print. Curr Mol Pharmacol. 2021. PMID: 33494692
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