Sharma S - Search Results

1

Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges.

Sharma S, Brosh RM Jr. Sharma S, et al. PLoS One. 2007 Dec 12;2(12):e1297. doi: 10.1371/journal.pone.0001297. PLoS One. 2007. PMID: 18074021 Free PMC article.

2

The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein.

Sharma S, Sommers JA, Driscoll HC, Uzdilla L, Wilson TM, Brosh RM Jr. Sharma S, et al. J Biol Chem. 2003 Jun 27;278(26):23487-96. doi: 10.1074/jbc.M212798200. Epub 2003 Apr 18. J Biol Chem. 2003. PMID: 12704184

3

WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork.

Sharma S, Otterlei M, Sommers JA, Driscoll HC, Dianov GL, Kao HI, Bambara RA, Brosh RM Jr. Sharma S, et al. Mol Biol Cell. 2004 Feb;15(2):734-50. doi: 10.1091/mbc.e03-08-0567. Epub 2003 Dec 2. Mol Biol Cell. 2004. PMID: 14657243 Free PMC article.

4

Stimulation of flap endonuclease-1 by the Bloom's syndrome protein.

Sharma S, Sommers JA, Wu L, Bohr VA, Hickson ID, Brosh RM Jr. Sharma S, et al. J Biol Chem. 2004 Mar 12;279(11):9847-56. doi: 10.1074/jbc.M309898200. Epub 2003 Dec 19. J Biol Chem. 2004. PMID: 14688284

5

In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication.

Sharma S, Sommers JA, Brosh RM Jr. Sharma S, et al. Hum Mol Genet. 2004 Oct 1;13(19):2247-61. doi: 10.1093/hmg/ddh234. Epub 2004 Jul 28. Hum Mol Genet. 2004. PMID: 15282207

6

p53 modulates RPA-dependent and RPA-independent WRN helicase activity.

Sommers JA, Sharma S, Doherty KM, Karmakar P, Yang Q, Kenny MK, Harris CC, Brosh RM Jr. Sommers JA, et al. Among authors: sharma s. Cancer Res. 2005 Feb 15;65(4):1223-33. doi: 10.1158/0008-5472.CAN-03-0231. Cancer Res. 2005. PMID: 15735006

7

Analysis of the DNA substrate specificity of the human BACH1 helicase associated with breast cancer.

Gupta R, Sharma S, Sommers JA, Jin Z, Cantor SB, Brosh RM Jr. Gupta R, et al. Among authors: sharma s. J Biol Chem. 2005 Jul 8;280(27):25450-60. doi: 10.1074/jbc.M501995200. Epub 2005 May 5. J Biol Chem. 2005. PMID: 15878853

8

RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination.

Doherty KM, Sharma S, Uzdilla LA, Wilson TM, Cui S, Vindigni A, Brosh RM Jr. Doherty KM, et al. Among authors: sharma s. J Biol Chem. 2005 Jul 29;280(30):28085-94. doi: 10.1074/jbc.M500265200. Epub 2005 May 9. J Biol Chem. 2005. PMID: 15886194

9

Biochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1.

Sharma S, Sommers JA, Choudhary S, Faulkner JK, Cui S, Andreoli L, Muzzolini L, Vindigni A, Brosh RM Jr. Sharma S, et al. J Biol Chem. 2005 Jul 29;280(30):28072-84. doi: 10.1074/jbc.M500264200. Epub 2005 May 16. J Biol Chem. 2005. PMID: 15899892

10

DNA helicases as targets for anti-cancer drugs.

Sharma S, Doherty KM, Brosh RM Jr. Sharma S, et al. Curr Med Chem Anticancer Agents. 2005 May;5(3):183-99. doi: 10.2174/1568011053765985. Curr Med Chem Anticancer Agents. 2005. PMID: 15992349 Review.

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