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Epidermal growth factor receptor mutations in lung cancer.
Sharma SV, Bell DW, Settleman J, Haber DA. Sharma SV, et al. Nat Rev Cancer. 2007 Mar;7(3):169-81. doi: 10.1038/nrc2088. Nat Rev Cancer. 2007. PMID: 17318210 Review.
Targeting the cyclin E-Cdk-2 complex represses lung cancer growth by triggering anaphase catastrophe.
Galimberti F, Thompson SL, Liu X, Li H, Memoli V, Green SR, DiRenzo J, Greninger P, Sharma SV, Settleman J, Compton DA, Dmitrovsky E. Galimberti F, et al. Among authors: sharma sv. Clin Cancer Res. 2010 Jan 1;16(1):109-20. doi: 10.1158/1078-0432.CCR-09-2151. Epub 2009 Dec 22. Clin Cancer Res. 2010. PMID: 20028770 Free PMC article.
Inhibition of Casein Kinase 1 Alpha Prevents Acquired Drug Resistance to Erlotinib in EGFR-Mutant Non-Small Cell Lung Cancer.
Lantermann AB, Chen D, McCutcheon K, Hoffman G, Frias E, Ruddy D, Rakiec D, Korn J, McAllister G, Stegmeier F, Meyer MJ, Sharma SV. Lantermann AB, et al. Among authors: sharma sv. Cancer Res. 2015 Nov 15;75(22):4937-48. doi: 10.1158/0008-5472.CAN-15-1113. Epub 2015 Oct 21. Cancer Res. 2015. PMID: 26490646
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations.
Sharma SV, Lee DY, Li B, Quinlan MP, Takahashi F, Maheswaran S, McDermott U, Azizian N, Zou L, Fischbach MA, Wong KK, Brandstetter K, Wittner B, Ramaswamy S, Classon M, Settleman J. Sharma SV, et al. Cell. 2010 Apr 2;141(1):69-80. doi: 10.1016/j.cell.2010.02.027. Cell. 2010. PMID: 20371346 Free PMC article.
Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents.
Sharma SV, Haber DA, Settleman J. Sharma SV, et al. Nat Rev Cancer. 2010 Apr;10(4):241-53. doi: 10.1038/nrc2820. Epub 2010 Mar 19. Nat Rev Cancer. 2010. PMID: 20300105 Review.
Exploiting the balance between life and death: targeted cancer therapy and "oncogenic shock".
Sharma SV, Settleman J. Sharma SV, et al. Biochem Pharmacol. 2010 Sep 1;80(5):666-73. doi: 10.1016/j.bcp.2010.03.001. Epub 2010 Mar 6. Biochem Pharmacol. 2010. PMID: 20211150 Review.
Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors.
McDermott U, Ames RY, Iafrate AJ, Maheswaran S, Stubbs H, Greninger P, McCutcheon K, Milano R, Tam A, Lee DY, Lucien L, Brannigan BW, Ulkus LE, Ma XJ, Erlander MG, Haber DA, Sharma SV, Settleman J. McDermott U, et al. Among authors: sharma sv. Cancer Res. 2009 May 1;69(9):3937-46. doi: 10.1158/0008-5472.CAN-08-4327. Epub 2009 Apr 14. Cancer Res. 2009. PMID: 19366796 Free PMC article.
Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma.
Plentz R, Park JS, Rhim AD, Abravanel D, Hezel AF, Sharma SV, Gurumurthy S, Deshpande V, Kenific C, Settleman J, Majumder PK, Stanger BZ, Bardeesy N. Plentz R, et al. Among authors: sharma sv. Gastroenterology. 2009 May;136(5):1741-9.e6. doi: 10.1053/j.gastro.2009.01.008. Epub 2009 Jan 14. Gastroenterology. 2009. PMID: 19208345 Free PMC article.
Reduced Erlotinib sensitivity of epidermal growth factor receptor-mutant non-small cell lung cancer following cisplatin exposure: a cell culture model of second-line erlotinib treatment.
Chin TM, Quinlan MP, Singh A, Sequist LV, Lynch TJ, Haber DA, Sharma SV, Settleman J. Chin TM, et al. Among authors: sharma sv. Clin Cancer Res. 2008 Nov 1;14(21):6867-76. doi: 10.1158/1078-0432.CCR-08-0093. Clin Cancer Res. 2008. PMID: 18980981 Free PMC article.
ErbBs in lung cancer.
Sharma SV, Settleman J. Sharma SV, et al. Exp Cell Res. 2009 Feb 15;315(4):557-71. doi: 10.1016/j.yexcr.2008.07.026. Epub 2008 Aug 6. Exp Cell Res. 2009. PMID: 18721806 Review.
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