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The RNAi revolution.
Novina CD, Sharp PA. Novina CD, et al. Among authors: sharp pa. Nature. 2004 Jul 8;430(6996):161-4. doi: 10.1038/430161a. Nature. 2004. PMID: 15241403 No abstract available.
RNAi and double-strand RNA.
Sharp PA. Sharp PA. Genes Dev. 1999 Jan 15;13(2):139-41. Genes Dev. 1999. PMID: 9925636 Review. No abstract available.
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals.
Zamore PD, Tuschl T, Sharp PA, Bartel DP. Zamore PD, et al. Among authors: sharp pa. Cell. 2000 Mar 31;101(1):25-33. doi: 10.1016/S0092-8674(00)80620-0. Cell. 2000. PMID: 10778853
siRNA-directed inhibition of HIV-1 infection.
Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman RG, Lieberman J, Shankar P, Sharp PA. Novina CD, et al. Among authors: sharp pa. Nat Med. 2002 Jul;8(7):681-6. doi: 10.1038/nm725. Epub 2002 Jun 3. Nat Med. 2002. PMID: 12042777
Gene silencing in mammals by small interfering RNAs.
McManus MT, Sharp PA. McManus MT, et al. Among authors: sharp pa. Nat Rev Genet. 2002 Oct;3(10):737-47. doi: 10.1038/nrg908. Nat Rev Genet. 2002. PMID: 12360232 Review.
Killing the messenger: short RNAs that silence gene expression.
Dykxhoorn DM, Novina CD, Sharp PA. Dykxhoorn DM, et al. Among authors: sharp pa. Nat Rev Mol Cell Biol. 2003 Jun;4(6):457-67. doi: 10.1038/nrm1129. Nat Rev Mol Cell Biol. 2003. PMID: 12778125 Review.
Transcriptional silencing of a transgene by RNAi in the soma of C. elegans.
Grishok A, Sinskey JL, Sharp PA. Grishok A, et al. Among authors: sharp pa. Genes Dev. 2005 Mar 15;19(6):683-96. doi: 10.1101/gad.1247705. Epub 2005 Mar 1. Genes Dev. 2005. PMID: 15741313 Free PMC article.
Herpesviruses throw a curve ball: new insights into microRNA biogenesis and evolution.
Neilson JR, Sharp PA. Neilson JR, et al. Among authors: sharp pa. Nat Methods. 2005 Apr;2(4):252-4. doi: 10.1038/nmeth0405-252. Nat Methods. 2005. PMID: 15782215 No abstract available.
MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells.
Ebert MS, Neilson JR, Sharp PA. Ebert MS, et al. Among authors: sharp pa. Nat Methods. 2007 Sep;4(9):721-6. doi: 10.1038/nmeth1079. Epub 2007 Aug 12. Nat Methods. 2007. PMID: 17694064 Free PMC article.
Small RNAs tell big stories in Whistler.
Seila AC, Sharp PA. Seila AC, et al. Among authors: sharp pa. Nat Cell Biol. 2008 Jun;10(6):630-3. doi: 10.1038/ncb0608-630. Nat Cell Biol. 2008. PMID: 18521067
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