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The regulation of INK4/ARF in cancer and aging.
Kim WY, Sharpless NE. Kim WY, et al. Among authors: sharpless ne. Cell. 2006 Oct 20;127(2):265-75. doi: 10.1016/j.cell.2006.10.003. Cell. 2006. PMID: 17055429 Review.
ROS as a tumour suppressor?
Ramsey MR, Sharpless NE. Ramsey MR, et al. Among authors: sharpless ne. Nat Cell Biol. 2006 Nov;8(11):1213-5. doi: 10.1038/ncb1106-1213. Nat Cell Biol. 2006. PMID: 17077852 No abstract available.
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.
Chang J, Wang Y, Shao L, Laberge RM, Demaria M, Campisi J, Janakiraman K, Sharpless NE, Ding S, Feng W, Luo Y, Wang X, Aykin-Burns N, Krager K, Ponnappan U, Hauer-Jensen M, Meng A, Zhou D. Chang J, et al. Among authors: sharpless ne. Nat Med. 2016 Jan;22(1):78-83. doi: 10.1038/nm.4010. Epub 2015 Dec 14. Nat Med. 2016. PMID: 26657143 Free PMC article.
Defective cell cycle checkpoint functions in melanoma are associated with altered patterns of gene expression.
Kaufmann WK, Nevis KR, Qu P, Ibrahim JG, Zhou T, Zhou Y, Simpson DA, Helms-Deaton J, Cordeiro-Stone M, Moore DT, Thomas NE, Hao H, Liu Z, Shields JM, Scott GA, Sharpless NE. Kaufmann WK, et al. Among authors: sharpless ne. J Invest Dermatol. 2008 Jan;128(1):175-87. doi: 10.1038/sj.jid.5700935. Epub 2007 Jun 28. J Invest Dermatol. 2008. PMID: 17597816 Free PMC article.
Ink4a/Arf expression is a biomarker of aging.
Krishnamurthy J, Torrice C, Ramsey MR, Kovalev GI, Al-Regaiey K, Su L, Sharpless NE. Krishnamurthy J, et al. Among authors: sharpless ne. J Clin Invest. 2004 Nov;114(9):1299-307. doi: 10.1172/JCI22475. J Clin Invest. 2004. PMID: 15520862 Free PMC article.
Constitutive Ras signaling and Ink4a/Arf inactivation cooperate during the development of B-ALL in mice.
Sewastianik T, Jiang M, Sukhdeo K, Patel SS, Roberts K, Kang Y, Alduaij A, Dennis PS, Lawney B, Liu R, Song Z, Xiong J, Zhang Y, Lemieux ME, Pinkus GS, Rich JN, Weinstock DM, Mullighan CG, Sharpless NE, Carrasco RD. Sewastianik T, et al. Among authors: sharpless ne. Blood Adv. 2017 Nov 21;1(25):2361-2374. doi: 10.1182/bloodadvances.2017012211. eCollection 2017 Nov 28. Blood Adv. 2017. PMID: 29296886 Free PMC article.
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