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Concentrations of Pro-Inflammatory Cytokines Are Not Associated with Senescence Marker p16INK4a or Predictive of Intracellular Emtricitabine/Tenofovir Metabolite and Endogenous Nucleotide Exposures in Adults with HIV Infection.
Maas BM, Francis O, Mollan KR, Lee C, Cottrell ML, Prince HM, Sykes C, Trezza C, Torrice C, White N, Malone S, Hudgens MG, Sharpless NE, Dumond JB. Maas BM, et al. Among authors: sharpless ne. PLoS One. 2016 Dec 30;11(12):e0168709. doi: 10.1371/journal.pone.0168709. eCollection 2016. PLoS One. 2016. PMID: 28036343 Free PMC article. Clinical Trial.
p16INK4a , a Senescence Marker, Influences Tenofovir/Emtricitabine Metabolite Disposition in HIV-Infected Subjects.
Dumond JB, Collins JW, Cottrell ML, Trezza CR, Prince H, Sykes C, Torrice C, White N, Malone S, Wang R, Patterson KB, Sharpless NE, Forrest A. Dumond JB, et al. Among authors: sharpless ne. CPT Pharmacometrics Syst Pharmacol. 2017 Feb;6(2):120-127. doi: 10.1002/psp4.12150. Epub 2016 Dec 26. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 28019088 Free PMC article. Clinical Trial.
Population Pharmacokinetics Modeling of Unbound Efavirenz, Atazanavir, and Ritonavir in HIV-Infected Subjects With Aging Biomarkers.
Dumond JB, Chen J, Cottrell M, Trezza CR, Prince H, Sykes C, Torrice C, White N, Malone S, Wang R, Patterson KB, Sharpless NE, Forrest A. Dumond JB, et al. Among authors: sharpless ne. CPT Pharmacometrics Syst Pharmacol. 2017 Feb;6(2):128-135. doi: 10.1002/psp4.12151. Epub 2016 Dec 29. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 28032946 Free PMC article. Clinical Trial.
Tenofovir/emtricitabine metabolites and endogenous nucleotide exposures are associated with p16(INK4a) expression in subjects on combination therapy.
Dumond JB, Francis O, Cottrell M, Trezza C, Prince HM, Mollan K, Sykes C, Torrice C, White N, Malone S, Wang R, Van Dam C, Patterson KB, Hudgens MG, Sharpless NE, Forrest A. Dumond JB, et al. Among authors: sharpless ne. Antivir Ther. 2016;21(5):441-5. doi: 10.3851/IMP3017. Epub 2016 Jan 5. Antivir Ther. 2016. PMID: 26731175 Free PMC article.
Ink4a/Arf expression is a biomarker of aging.
Krishnamurthy J, Torrice C, Ramsey MR, Kovalev GI, Al-Regaiey K, Su L, Sharpless NE. Krishnamurthy J, et al. Among authors: sharpless ne. J Clin Invest. 2004 Nov;114(9):1299-307. doi: 10.1172/JCI22475. J Clin Invest. 2004. PMID: 15520862 Free PMC article.
Role of senescence marker p16 INK4a measured in peripheral blood T-lymphocytes in predicting length of hospital stay after coronary artery bypass surgery in older adults.
Pustavoitau A, Barodka V, Sharpless NE, Torrice C, Nyhan D, Berkowitz DE, Shah AS, Bandeen Roche KJ, Walston JD. Pustavoitau A, et al. Among authors: sharpless ne. Exp Gerontol. 2016 Feb;74:29-36. doi: 10.1016/j.exger.2015.12.003. Epub 2015 Dec 9. Exp Gerontol. 2016. PMID: 26692418 Free PMC article.
194 results