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The MEK/ERK cascade: from signaling specificity to diverse functions.
Shaul YD, Seger R. Shaul YD, et al. Biochim Biophys Acta. 2007 Aug;1773(8):1213-26. doi: 10.1016/j.bbamcr.2006.10.005. Epub 2006 Oct 19. Biochim Biophys Acta. 2007. PMID: 17112607 Review.
Specific phosphorylation and activation of ERK1c by MEK1b: a unique route in the ERK cascade.
Shaul YD, Gibor G, Plotnikov A, Seger R. Shaul YD, et al. Genes Dev. 2009 Aug 1;23(15):1779-90. doi: 10.1101/gad.523909. Genes Dev. 2009. PMID: 19651986 Free PMC article.
ERK1c regulates Golgi fragmentation during mitosis.
Shaul YD, Seger R. Shaul YD, et al. J Cell Biol. 2006 Mar 13;172(6):885-97. doi: 10.1083/jcb.200509063. J Cell Biol. 2006. PMID: 16533948 Free PMC article.
Use of inhibitors in the study of MAPK signaling.
Shaul YD, Seger R. Shaul YD, et al. Methods Mol Biol. 2004;250:113-26. doi: 10.1385/1-59259-671-1:113. Methods Mol Biol. 2004. PMID: 14755084 No abstract available.
Extracellular signal-regulated kinase 1c (ERK1c), a novel 42-kilodalton ERK, demonstrates unique modes of regulation, localization, and function.
Aebersold DM, Shaul YD, Yung Y, Yarom N, Yao Z, Hanoch T, Seger R. Aebersold DM, et al. Among authors: shaul yd. Mol Cell Biol. 2004 Nov;24(22):10000-15. doi: 10.1128/MCB.24.22.10000-10015.2004. Mol Cell Biol. 2004. PMID: 15509801 Free PMC article.
The detection of MAPK signaling.
Shaul Y, Seger R. Shaul Y, et al. Curr Protoc Cell Biol. 2005 Oct;Chapter 14:Unit 14.3. doi: 10.1002/0471143030.cb1403s28. Curr Protoc Cell Biol. 2005. PMID: 18228462
The detection of MAPK signaling.
Shaul Y, Seger R. Shaul Y, et al. Curr Protoc Mol Biol. 2006 Feb;Chapter 18:Unit 18.12. doi: 10.1002/0471142727.mb1812s73. Curr Protoc Mol Biol. 2006. PMID: 18265377
The polyomavirus middle T-antigen oncogene activates the Hippo pathway tumor suppressor Lats in a Src-dependent manner.
Shanzer M, Ricardo-Lax I, Keshet R, Reuven N, Shaul Y. Shanzer M, et al. Oncogene. 2015 Aug 6;34(32):4190-8. doi: 10.1038/onc.2014.347. Epub 2014 Nov 3. Oncogene. 2015. PMID: 25362852
The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl.
Reuven N, Adler J, Meltser V, Shaul Y. Reuven N, et al. Cell Death Differ. 2013 Oct;20(10):1330-40. doi: 10.1038/cdd.2013.83. Epub 2013 Jul 12. Cell Death Differ. 2013. PMID: 23852372 Free PMC article.
Nuclear import and DNA-binding activity of RFX1. Evidence for an autoinhibitory mechanism.
Katan-Khaykovich Y, Shaul Y. Katan-Khaykovich Y, et al. Eur J Biochem. 2001 May;268(10):3108-16. doi: 10.1046/j.1432-1327.2001.02211.x. Eur J Biochem. 2001. PMID: 11358531
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